Haematological System Flashcards
name
What is the function of the haematological
system?
Deliver substance for Cellular
Metabolism,
Remove waste,
Defend against Micro-organisms and injury,
maintain acid-base balance
Cellular components Erythrocytes Most abundant cell in the body Responsible for tissue oxygenation Biconcavity and reversible deformity 120-day life cycle
what is the blood made of?
Composition of blood ➢ 90% water and 10% solutes ➢ 5.5L ➢ pH 7.35-7.45 ➢ Plasma • 50–55% of the blood volume • Organic and inorganic elements
What are some plasma proteins?
• Albumins
Carriers and control the plasma oncotic pressure
• Globulins
Carrier proteins and immunoglobulins (antibodies)
• Clotting factors
Mainly Fibrinogen
What are Leucocytes?
Leucocytes (white blood cells)
• Defend the body against infection and remove debris
what are Granulocytes?
Neutrophils
• Phagocytes in early inflammation
• Granulocytes
Membrane-bound granules in their cytoplasm
Granules contain enzymes capable of destroying microorganisms
Inflammatory and immune functions
Capable of amoeboid movement (diapedesis)
what are Eosinophils
- Eosinophils ingest antigen-antibody complexes
- Induced by IgE hypersensitivity
- Attack parasites
what are Basophils
Structurally and functionally similar to mast cells
• Cytoplasmic granules contain vasoactive amines
- Histamine
what are mast cells
Inflammatory process
• Contain histamine and heparin
what is Agranulocytes
➢ Monocytes and macrophages make up the mononuclear phagocyte system (MPS) ➢ Monocytes ➢ Macrophages ➢ Lymphocytes ➢ Natural killer (NK) cells
what are platelets
Disc-shaped cytoplasmic fragments of megakaryocytes ➢ Essential for blood coagulation and control of bleeding ➢ Survive for 10 days