H pylori, Y enterocolitica Flashcards
Uses invasin for M cells
Yersinia enterocolitica
mimics appendicitis
Yersinia enterocolitica
Grows slow at cool temps, can be spread by transfusion
Yersinia enterocolitica
Causes ulcers
Helicobacter pylori
H pylori virulence
Urease raises pH and allows growth in stomache
human reservoir with smoking risk factor
H pylori
Detection with CLO test
H pylori
(detects urease activity)
microaerophil environment with 7 day incubation
H pylori
YOP virulon
Yersinia enterocolitica
made when Ca is low
Yersinia enterocollitica treatment
Supportive is remains in GI
Aminoglycosides, tetracyclines if systemic
Why can’t you find Y enterocolitica on MacConkey
Outgrown by other bacteria
so slow, culture is retrospective
Pork
Yersinia enterocolitica
infects animals from environment
Y entericolitica transmission
fecal-oral
winter
Gram (-) coccobacillus
Y entericolitica
Detected with Geisma stain
H pylori
Grows under mucous in stomach
H pylori
cag PGI
H pylori
messes with cell signaling, produce less acid
Organisms that bind to and communicate with host, don’t enter cell
EPEC, EHEC, H pylori
Multiple adhesions to avoid damage
H pylori, moves to edge of ulcer
What happens if an M cell takes up yersinia enteroltica?
Y entericolitica starts expressing YOP and M cell kills itself (at 37 deg with low Ca)