H/E Lecture 14 Flashcards
1
Q
Where does CT come from?
A
Mesenchyme, which comes from mesoderm and the neural crest
2
Q
What do mesenchymal-like cells do in CT?
A
They are stem-like cells that help with cell renewal.
3
Q
What do fibroblasts and fibrocytes do?
A
Secrete and synthesize all ECM components.
fibroblasts are more active and are used for growth and repair following an injury
fibrocytes are fewer cells , have reduced activity, and maintain the ECM
4
Q
What are the resident cells of the ECM?
A
Mesenchymal cells
Fibroblasts
Macrophages and mast cells
Adipocytes
5
Q
Describe mast cells
A
Centrally located nucleus Many dark granules fill cytoplasm Mediator of inflammation Releases heparin an anticoagulant Histamine increases vascular permeability and causes intense smooth muscle contraction and mucus secretion Cytokines attract WBC
6
Q
What are the transient cells of the CT?
A
WBCs and plasma cells
7
Q
Describe plasma cells
A
Tear drop cell, eccentric nucleus, clock-face or cartwheel pattern nucleus, negative golgi
Secretes antibodies
