Gynaecology - Signs and Symptoms Flashcards

1
Q

POP (pelvic organ prolapse) symptoms

A
  • Mild genital prolapse – may be asymptomatic + an incidental finding
  • Symptoms are related to the site + type of prolapse

• Vagina/general symptoms can be common to all types of prolapse
o Sensation of pressure/fullness/heaviness
o Sensation of a bulge/protrusion/”something coming down”
o Seeing or feeling a bulge/protrusion
o Difficulty retaining tampons
o Spotting (in the presence of ulceration of the prolapse)

• Urinary symptoms
o Recurrent UTI
o Incontinence
o Frequency
o Urgency
o Feeling of incomplete bladder emptying
o Weak/prolonged urinary stream
o Need to reduce prolapse manually before voiding
o Need to change position to start or complete voiding

• Bowel symptoms
o Constipation/straining
o Urgency of stool
o Incontinence of flatus or stool
o Incomplete evacuation
o Splinting – The need to apply digital pressure to the perineum or posterior vaginal wall to enable defecation
o Digital evacuation necessary in order to pass a stool

•	Coital difficulty
o	Dyspareunia
o	Loss of vaginal sensation
o	Vaginal flatus
o	Loss of arousal
o	Change in body image
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Symptoms of overactive bladder syndrome

A
  • Urgency that is difficult to delay
  • Urge incontinence
  • Frequency
  • Nocturia
  • Abdominal discomfort
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Signs and symptoms of PID (pelvic inflammatory disease)

A

• Asymptomatic – infertility +/- chronic pelvic pain

• Acutely
• Bilateral lower abdominal pain/tenderness
• Deep dyspareunia
• Abnormal vaginal bleeding (PCB, IMB, menorrhagia)
• Vaginal or cervical discharge is purulent
• Fever>38 (but may be apyrexial)
Signs
• Mucopurulent cervical discharge + cervicitis seen on speculum examination
• Cervical motion tenderness + adnexal tenderness on bimanual vagina examination
• N+V
• Urinary symptoms
• Proctitis
• Adnexal mass

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Bartholin’s cyst signs and symptoms

A

Symptoms
• Woman may find it uncomfortable to walk or sit
• Superficial dyspareunia
• Vaginal discharge – esp. in women with STIs

Signs
•	Cysts or abscesses are usually unilateral 
o	Unilateral labial mass
o	Cyst = soft, fluctuant, non-tender
o	Abscess = tense, hard, erythema
  • Onset of abscess is rapid – days/hours
  • Labial oedema before a swelling forms

• Swelling may be very painful
o Wide legged gait
o Uncomfortable for pt to sit

  • Spontaneous bursting of the cyst or abscess – sudden relief of pain
  • Palpable inguinal nodes, fever if infected
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Endometriosis symptoms and signs

A

Symptoms
• Appearance or worsening of symptoms at the time of menstruation or just prior to it - ?endometriosis

•	Common symptoms
o	Dysmenorrhoea (no menorrhagia differentiates this from fibroids)
o	Dyspareunia
o	Cyclical or chronic pelvic pain
o	Subfertility/Infertility 

• Other symptoms
o Period-related or cyclical GI symptoms – painful bowel movements
o Period-related or cyclical urinary symptoms – haematuria, dysuria
o Cyclical pain or bleeding e.g. epistaxis, haemoptysis at extrapelvic sites
o Menstrual irregularity
o Abdominal pain, low back pain
o Painful defecation, Bloating, Constipation
o lethargy

•	Less common symptoms 
o	Cyclical rectal bleeding
o	Menorrhagia
o	Diarrhoea
o	Haematuria 

Signs
• Examination is often normal

• There may be
o Posterior fornix or adnexal tenderness
o Palpable nodules in posterior fornix or adnexal masses – endometriosis can cause cystic lesions on the ovaries - chocolate cysts
o Bluish haemorrhagic nodules visible in the posterior fornix

  • Inflammation
  • Pain
  • Formation of adhesions
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Fibroids symptoms and signs

A
  • Most are asymptomatic
  • Lethargy
  • Pallor
  • Menorrhagia (larger fibroids)
  • IMB (pedunculated submucosal fibroids)
  • Pelvic pain
•	Sx of enlarged uterus
o	Lower abdominal discomfort
o	Abdominal swelling
o	Heaviness 
o	Constipation – pressure on bowel
o	Urinary symptoms – pressure on bladder 

• During pregnancy
o Acute pain - Fibroid degeneration
o Recurrent miscarriage
o Infertility (only with submucous fibroids – their removal restores fertility to baseline rates)

Signs
• Can cause significant morbidity incl. prolonged or heavy menstrual bleeding, pelvic pressure or pain, can contribute to reproductive dysfunction
• Iron deficiency anaemia
• Palpable abdominal mass arising from the pelvis
• Bimanual palpation – Enlarged, irregular, firm, non-tender uterus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Signs and symptoms of cervical polyps

A
  • Asymptomatic
  • Small bleeding and discharge
  • PCB
  • Contact bleeding e.g. postcoital bleeding, postvaginal examination bleeding
  • Abnormal bleeding – during intercourse, heavy menstrual periods, IMB, postmenopausal bleeding
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Signs and symptoms of cervical ectropion

A

IMB
PCB
Increased discharge
Contact bleeding e.g. postcoital bleeding, postvaginal examination bleeding

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Signs and symptoms of endometrial polyp

A

IMB - Usually hx of irregular spotting and bleeding between menstrual periods
?infertility

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Menopause signs and sympotms

A

• Menstrual irregularity
o Changes in menstrual cycle which may last for up to four years
o The cycle may lengthen to many months or shorten to 2-3 weeks
o Increase in the amount of menstrual blood loss is common
o Approximately 10% of women have an abrupt cessation of periods
o Persistent amenorrhoea – often initial oligomenorrhea/irregular or shortened cycles

• Vasomotor symptoms
o Hot flushes, night sweats, palpitations, headaches
o Hallmark symptoms
o Hot flushes commonly affect the face, head, neck and chest + last a few minutes
o (caused by loss of homeostasis by the central thermoregulatory centre)

• Urogenital
o Urogenital atrophy
o Dyspareunia, vaginal discomfort and dryness, vaginal irritation
o Recurrent lower UTI, urinary incontinence, frequency, dysuria
o Urinary symptoms may not manifest until 5-10 years after menopause
o Urogenital atrophy = thinning and shrinking tissues of the vulva, vagina, urethra, bladder cause by oestrogen deficiency

• Sleep disturbance
o Most common symptom reported by women

• Psychological
o Anxiety, nervousness, irritability, lethargy, memory loss, difficulty concentrating
o These present first

• Loss of libido
o Hormonal factors – oestrogen, progesterone, testosterone have all been implicated
o Vaginal dryness, loss of self-image, psychosocial factors

• Musculoskeletal symptoms
o Joint + muscle pain

• Other changes
o Brittle nails, thinning of the skin, hair loss, generalised aches and pains
o Due to falling oestrogen levels

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Symptoms and signs of atrophic vaginitis

A
  • Vaginal dryness
  • Burning or itching of the vagina/vulva
  • Dyspareunia
  • Vaginal discharge (usually white or yellow)
  • Vaginal bleeding or postcoital bleeding
•	Urinary symptoms
o	Increased frequency
o	Nocturia
o	Dysuria
o	Recurrent UTI
o	Stress incontinence
o	Urgency 

• External genitalia - reduced pubic hair, reduced turgor or elasticity, arrow introitus

•	Vaginal examination
o	Thin mucosa with diffuse erythema
o	Occasional petechiae or ecchymoses
o	Cracks or fissures 
o	Dryness
o	Lack of vaginal/rugal folds
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Signs and symptoms of Asherman’s syndrome

A
  • Irregular periods
  • Reduced menstrual flow
  • Increased cramping + cyclical abdominal pain

• Amenorrhoea
o Either due to complete destruction of the uterine lining or by obstruction of the cervix or lower portion of the uterus due to adhesions – menses are either retained in the uterus or flow into the abdominal cavity causing endometriosis

• Some pt may have normal periods

• Amenorrhoea + pain
o Pain may indicate that menstruation is occurring but the blood cannot exit the uterus because the cervix is blocked by adhesions
o This can also cause retrograde menstruation (menstruation blood that flows backwards into the fallopian tubes instead of being expelled from the body) - retrograde menstruation proposed as a RF for endometriosis

  • Recurrent miscarriage
  • Infertility
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Why might some women feel dizzy and have a slow HR while they are miscarrying?

A

• If a woman is having miscarriage + the products of conception are coming through the cervix, the cervical excitation can cause parasympathetic stimulation + a bradycardia, even if there is a blood loss

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Gestational trophoblastic disease symptoms and signs

A

• Irregular vaginal bleeding
o Painless
o Any woman who develops persistent vaginal bleeding after a pregnancy event is at risk of having GTN
o Excessive vaginal bleeding can be associated with molar pregnancy

  • Positive pregnancy test
  • Supporting ultrasonographic evidence

o Excessive uterine enlargement (uterus is large for dates)
o Abdominal distension due to theca lutein cysts – uterus larger than expected for GA
o Hyperemesis (increased HCG)
o Hyperthyroidism (from high hcg mimicking TSH)
o Early-onset pre-eclampsia

o O/E – excessive uterine size for gestation

• GTN – should be considered in any woman developing acute respiratory or neurological symptoms after pregnancy
• Presentations due to metastatic disease affecting the lungs or brain
o Haemoptysis
o Seizures

• Other symptoms of malignancy
o Persistent PV bleeding, hyperemesis, lower abdominal pain
o Lung mets – haemoptysis, dyspnoea, pleuritic pain
o Bladder/bowel – haematuria, PR bleeding

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

PCOS signs and symptoms

A

• Commonest presentation
o Infertility
o Menstrual irregularities (oligomenorrhoea or amenorrhoea)
 Oligomenorrhoea = <9 periods per year
 Prolonged amenorrhoea = <1 period every 3 months (oligomenorrhoea >3 months)
o Hirsutism
 Upper lips, lower abdomen
 Male pattern hair loss – tinning of hair starting from the crown of the head (alopecia)

  • Acne
  • Overweight/obesity or difficulty losing weight
  • Hypertension
  • Acanthosis nigricans (dark velvety patches in the creases of the neck, groin, underarms)  sign of severe insulin resistance
  • Occasionally, clitoromegaly, increased muscle mass, deep voice
  • Sleep apnoea
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Endometrial hyperplasia signs and symptoms

A

• Abnormal uterine bleeding

o	Heavy menstrual bleeding
o	Intermenstrual bleeding
o	Irregular bleeding
o	Unscheduled bleeding on HRT
o	Post-menopausal bleeding
17
Q

Signs and Symptoms of endometrial cancer

A

• Post-menopausal bleeding
o Endometrial cancer until proven otherwise
o As opposed to ovarian cancer which is more associated with palpable masses

  • Irregularities of the menstrual cycle
  • Uterine mass, fixed uterus, adnexal mass indicating extra-uterine disease
  • Metastasises to para-aortic LNs

• Speculum
o Unless disease is well advanced there is unlikely to be any physical abnormality
o Pipelle endometrial biopsy can also be done

18
Q

Benign ovarian tumours symptoms and signs

A
  • Asymptomatic – chance finding on bimanual or TVUS
  • Dull ache in lower abdomen, lower back pain

• Torsion/infarction/haemorrhage
o Severe abdominal pain
o Torsion may be intermittent – intermittent episodes of severe pain
o Ovarian torsion – complication of persistent masses in pregnancy

•	Rupture
o	Severe abdominal pain
o	Fever
o	Peritonitis
o	Shock
o	Rupture of mucinous cystadenomas – may disseminate cells which continue to secrete mucin + cause death by binding up the viscera – pseudomyxoma peritonei 
  • Dyspareunia
  • Swollen abdomen with palpable mass arising out of the pelvis – dull to percussion, does no disappear if the bladder is emptied

• Pressure effects
o Bladder – urinary frequency
o Venous return – varicose veins, leg oedema

• Ascites – Meig’s syndrome– fibromas
o Benign ovarian fibroma
o Ascites
o R-sided pleural effusion

• Endocrine – hormone secreting tumours – virilisation, menstrual irregularities, postmenopausal bleeding

(((• Symptoms suggestive of ovarian malignancy – persistent abdominal distension, appetite change incl. increased/early satiety, pelvic or abdominal pain, increased urinary urgency +/or frequency)))

19
Q

Ovarian cancer signs and symptoms

A
  • Early symptoms may be subtle – presentation is often last
  • Almost 60% of patients present with advanced disease (Stage III or IV)
  • Insidious onset of symptoms
•	Early symptoms are vague
o	Abdominal discomfort
o	Abdominal distension
o	Bloating
o	Urinary frequency 
o	Dyspepsia 
o	Constitutional symptoms – fatigue, weight loss, anorexia, depression 

• Pelvic or abdominal mass that may be associated with pain

• Abdominal/pelvic/back pain
o Late sign
o Seen only with early disease that is complicated by torsion, rupture or infection

  • Can cause abnormal uterine bleeding
  • Ascites
  • Pleural effusion (1/3 of patients with ascites)

• Ovarian cancer mets
o To pelvic and peri-aortic lymph nodes
o Pelvic + abdominal peritoneum

• Tests in primary care to be carried out if the woman (esp. >50) reports having ay of the following symptoms on a persistent or frequent basis, particularly >12 times per month
o Persistent abdominal distension – “bloating”
o Early satiety +/or loss of appetite
o Pelvic or abdominal pain
o Increased UU and/or frequency
o Unexplained weight loss, fatigue, changes in bowel habit

20
Q

• Ovarian vs endometrial cancer presentation

A

o Ovarian = adnexal mass, no PV bleeding

o Endometrial = uterine mass + PMB

21
Q

Lichen sclerosus symptoms

A

• Asymptomatic – incidental finding, rare

• Itch
o Usually the first symptom
o Usually worse at night – can be severe + disturb sleep

  • Pain/soreness – if there are fissures or erosions
  • Dyspareunia – due to tightened skin
  • Urinary symptoms – due to tightened skin
  • Perineal lesions – common, may cause constipation
22
Q

Lichen sclerosus signs

A

• Hypopigmentation + atrophy – Pale white atrophic lesions affecting the vulva
o Thickened patches (porcelain white papules and plaques)
o Localised or in a figure of eight area around the vulva and anus – white shiny vulva
o May progress to crinkled white patches (like cigarette paper)

• Active lesions – areas of purpura/ecchymosis, hyperkeratosis or bullae (might be mistaken for sexual abuse)
o May be raised or thickened

  • Fissuring
  • Erosions, blistering is very rare

• Destructive scarring/loss of architecture
o Shrinking of the labia, loss of labia minor and/or midline fusion
o Narrowing of the introitus
o Clitoris may be obscured by adhesions – clitoral hood may be sealed over the clitoris so that it is buried
o Genital involvement does not occur – vagina + cervix are always spared

• Perianal lesions (30%)

• Extragenital sites
o LS elsewhere – Often on the upper trunk, neck, axillae, buttocks, lateral thighs
o More rarely – face, scalp, hands, feet, nails
o Oral lesions – extremely rare, can affect sites where there is cornified stratifies squamous epithelium – e.g. tongue, gingiva, hard palate

23
Q

FGM symptoms and signs

A
o	Constant pain
o	Bleeding
o	Cysts, abscesses
o	Dyspareunia
o	Incontinence
o	Depression, flashbacks, self-harm 
•	Recent FGM
o	Pain
o	Haemorrhage 
o	Infection
o	Urinary retention