Gynae - Endometrial Flashcards

1
Q

what is adenomyosis?

A

endometrial tissue in the myometrium (muscle)

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2
Q

who is more common to get adenomyosis?

A

later life

multiple pregnancies

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3
Q

features of adenomyosis?

A
dysmenorrhoea
menorrhagia
dysparaeunia 
inferility 
enlarged tender uterus
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4
Q

Ix for adenomyosis?

A

TVUS

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5
Q

Tx for adenomyosis?

A

tranxemic acid
mefanamic acid

COCP/mirena coil

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6
Q

what happens in endometriosis?

A

endometrial tissue located at sites other than the uterine cavity

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7
Q

common sites of endometriosis?

A

pouch of douglas
peritoneum
bladder
umbilicus

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8
Q

features of endometriosis?

A
menorrhagia
dysmenorrhoea
dyspareunia
chronic pain
cyclic pain 
suberfertility 
pelvic mass
bloating 
distension
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9
Q

Ix for endometriosis?

A

PV (fixed retroverted uterus)
swabs
TVUS
laparoscopy

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10
Q

Tx for endometriosis?

A
NSAIDs
COCP
GnRH agonists (goserulin)
surgery - ablation/hysterectomy
fertility Tx
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11
Q

what are fibroids?

A

benign tumours of the smooth muscle of the uterus (uterine leiomyomas)

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12
Q

what types of fibroids exist?

A

submucosal (endometrial)
subserosal (outer layer)
intramural (in myometrium)
pedunculated

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13
Q

features of fibroids?

A
menorrhagia
abdo pain worse during period
bloating 
urinary/bowel symptoms
deep dysparunia
infertility
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14
Q

Ix for fibroids?

A

abdo exam
PV (firm non tender uterus)
hysteroscopy
pelvic US

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15
Q

Tx for fibroids?

A

mirena/COCP (<3cm no distortion)

GnRH
to reduce size before surgery

myomectomy
hysterectomy
uterine artery embolisation

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16
Q

who can get fibroids with red degeneration? features?

A

pregnancy
abdo pain
low grade fever

17
Q

risk factors for endometrial cancer?

A
50-60yrs
obese
HNPCC
oestrogens
PCOS
nullparity
18
Q

features of endometrial cancer?

A

post menopausal bleed
irregular bleed
pelvic pain
irregular discharge

19
Q

what is the most common type of endometrial cancer? how does it occur?

A

endometrial adenocarcinoma

hyperplasia due to unopposed oestrogens

20
Q

Ix for endometrial cancer?

A

TVUS + biopsy
D+C
hysteroscopy
CT/MRI

21
Q

what are the normal endometrial mm size?

A

> 4 in postmenopausal
5 in HRT
16 in premenopausal

22
Q

Tx for endometrial cancer?

A

hyserectomy + bilateral salphingoopherectomy

+ radio
+ chemo

23
Q

Tx for endometrial hyperplasia?

A

mirena/progestogens

hysterectomy

24
Q

what is HNPCC?

A

lynch syndrome

colorectal + ovarian (endometriod/clear cell) + endometrial (adenocarcinoma)