Infertility + Assisted Conception Flashcards
what are the specifications people must follow before getting fertility Tx?
<4units/week 19-29 BMI no smoking no drugs rubella immunity smears HepB/C, HIV screen follicle count
0.4mg folic acid >12 wks
who gets IVF?
infertility >2yrs
pelvic disease
anovulatory/male factor infertility
pre implantation genetic diagnosis
who gets ICSI?
male infertility
man has genetic diagnosis (CF)
who gets IUI?
sexual problems
mild infertility
HIV diagnosis
endometriosis
what happens in ICSI?
sperm extracted from epididymis (obstructive) or testicles (non obstructive)
what happens in IVF?
down regulation (menopause) ovarian stimulation (GnRH to help follicle develop) oocyte collected fertilization embryo transfer
complications of IVF?
multiple preg ectopic miscarriage psychological ovarian hyperstimulation syndrome
features of ovarian hyperstimulation syndrome?
abdo pain bloating nausea diarrhoea breathless (pericardial effusion)
what is infertility?
failure to get pregnant after 12 months of regular unprotected sex
what is the normal testicular volume?
12-25mls
obstructive causes of male infertility?
CF
vasectomy
infection
non obstructive causes of male infertility?
mumps orchitis STIs chemo/radio tumours cryptoorchidism klenfelters XXY endocrine globozoospermia
Ix for male infertility?
semen analysis
endocrine profile (high LH/FSH + low testosterone is non obstructive e.g genetic)
chromosome analysis
US sccrotum
how many cycles of fertility Tx do people get?
up to 3
