gyn Flashcards
tumor marker for ovarian cancer
CA-125
MC type of ovarian cancer
epithelial carcinoma
which diagnostic test will remain positive after a persons first syphilis infection leading to false positive results and inaccuracy in diagnosing syphillis?
Fluorescent treponemal antibody absorption (FTA-ABS)
(a treponemal test)
how do you screen and diagnose syphilis
screen with non-treponemal tests- RPR or VRDL
Confirm with treponemal tests- EIA, TPHA ,Fluorescent treponemal antibody absorption (FTA-ABS)
what is the most specific test for syphilis when a chancre or condyloma latum is present?
Dark-field microscopy
You can get a false-positive results on VRDL or RPR due to what 3 conditions?
pregnancy
autoimmune disorders
other infections
what part of the menstrual cycle is a ruptured cyst most likely to occur
During the luteal phase, mid-menstrual cycle.
what is the MC location of the uterus in a patient with endometriosis
fixed or retroverted uterus
What is 1st and 2nd line tx for Lymphogranuloma venereum
1st line= doxycycline 100 mg orally BID x 21 days. 2ndline= erythromycin 500 mg orally QD x 21 days.
What is the MC type of vulvar cancer
squamous cell carcinoma (SCC)
tx for chanchroid caused by H. ducrei
Ceftriaxone IM
OR
Azithromycin 1g
what hormone is considered a causative factor in the development of fibrocystic breast disease?
Estrogen
(this is why fibrocystic breast dz resolves after menopause)
What is the preferred 1st line chemotherapy in women who have suboptimally cytoreduced disease after surgical cytoreduction for epithelial ovarian cancer.
Carboplatin and paclitaxel IV
In a patient with irregular menstrual cycles or unknown LMP, what should be the marker for repeating a urine HCG test?
the last date of intercourse should be used as the marker for repeating a urine pregnancy test.
A urine pregnancy test 14 days after last intercourse
what is the tx for unstable uterine bleeding
IV estrogen
What type of dx test should be used to dx GC/C
NAAT
what hormonal changes are seen in the menopausal trasition in regards to:
- Estrone
- Estradiol
- Testosterone
- FSH/LH
- Estrone: INCREASE
- Estradiol: DECREASE
- Testosterone: NO CHANGE
- FSH/LH: INCREASE
What changes are seen in menopause in regards to:
- Total cholesterol
- LDL
- Apolipoprotein B
- HDL
- Total cholesterol: HIGHER
- LDL: LOW
- Apolipoprotein B: LOW
- HDL: LOSS OF PROTECTIVE EFFECT
What 2 fetal positions are associated with lower external cephalic version success
- Longitudinal (AKA vertical- TV is better b/c dont have to rotate as much)
- Frank breech
What placenta location is a/w succesful external cephalic version? What location is a/w failure?
Success: posterior placenta
Failure: anterior placenta
What 2 situations are CI for external cephalic version
PLACENTA PREVIA
prior CD
Tx for PID (outpatient)?
Ceftriaxone and Doxy
What is the physiologic cascade triggered by stress in a pregnant patient which can lead to Preterm labor?
Increased ACTH–> Increased cortisol–> increased corticotropin-releasing hormone–> activates prostaglandins that cause cervical change and rupture of membranes
