gyn Flashcards

1
Q

tumor marker for ovarian cancer

A

CA-125

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2
Q

MC type of ovarian cancer

A

epithelial carcinoma

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3
Q

which diagnostic test will remain positive after a persons first syphilis infection leading to false positive results and inaccuracy in diagnosing syphillis?

A

Fluorescent treponemal antibody absorption (FTA-ABS)

(a treponemal test)

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4
Q

how do you screen and diagnose syphilis

A

screen with non-treponemal tests- RPR or VRDL

Confirm with treponemal tests- EIA, TPHA ,Fluorescent treponemal antibody absorption (FTA-ABS)

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5
Q

what is the most specific test for syphilis when a chancre or condyloma latum is present?

A

Dark-field microscopy

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6
Q

You can get a false-positive results on VRDL or RPR due to what 3 conditions?

A

pregnancy

autoimmune disorders

other infections

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7
Q

what part of the menstrual cycle is a ruptured cyst most likely to occur

A

During the luteal phase, mid-menstrual cycle.

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8
Q

what is the MC location of the uterus in a patient with endometriosis

A

fixed or retroverted uterus

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9
Q

What is 1st and 2nd line tx for Lymphogranuloma venereum

A

1st line= doxycycline 100 mg orally BID x 21 days. 2ndline= erythromycin 500 mg orally QD x 21 days.

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10
Q

What is the MC type of vulvar cancer

A

squamous cell carcinoma (SCC)

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11
Q

tx for chanchroid caused by H. ducrei

A

Ceftriaxone IM

OR

Azithromycin 1g

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12
Q

what hormone is considered a causative factor in the development of fibrocystic breast disease?

A

Estrogen

(this is why fibrocystic breast dz resolves after menopause)

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13
Q

What is the preferred 1st line chemotherapy in women who have suboptimally cytoreduced disease after surgical cytoreduction for epithelial ovarian cancer.

A

Carboplatin and paclitaxel IV

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14
Q

In a patient with irregular menstrual cycles or unknown LMP, what should be the marker for repeating a urine HCG test?

A

the last date of intercourse should be used as the marker for repeating a urine pregnancy test.

A urine pregnancy test 14 days after last intercourse

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15
Q

what is the tx for unstable uterine bleeding

A

IV estrogen

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16
Q

What type of dx test should be used to dx GC/C

A

NAAT

17
Q

what hormonal changes are seen in the menopausal trasition in regards to:

  • Estrone
  • Estradiol
  • Testosterone
  • FSH/LH
A
  • Estrone: INCREASE
  • Estradiol: DECREASE
  • Testosterone: NO CHANGE
  • FSH/LH: INCREASE
18
Q

What changes are seen in menopause in regards to:

  • Total cholesterol
  • LDL
  • Apolipoprotein B
  • HDL
A
  • Total cholesterol: HIGHER
  • LDL: LOW
  • Apolipoprotein B: LOW
  • HDL: LOSS OF PROTECTIVE EFFECT
19
Q

What 2 fetal positions are associated with lower external cephalic version success

A
  • Longitudinal (AKA vertical- TV is better b/c dont have to rotate as much)
  • Frank breech
20
Q
A
21
Q

What placenta location is a/w succesful external cephalic version? What location is a/w failure?

A

Success: posterior placenta

Failure: anterior placenta

22
Q

What 2 situations are CI for external cephalic version

A

PLACENTA PREVIA

prior CD

23
Q

Tx for PID (outpatient)?

A

Ceftriaxone and Doxy

24
Q

What is the physiologic cascade triggered by stress in a pregnant patient which can lead to Preterm labor?

A

Increased ACTH–> Increased cortisol–> increased corticotropin-releasing hormone–> activates prostaglandins that cause cervical change and rupture of membranes

25
Q

ovarian mass over what size increases risk for torsion?

A

>5cm

26
Q

tx for Lymphogranuloma venereum if pregnant or breastfeeding

A

erythromycin

(Doxy is first line for everyone else)

27
Q

what 3 meds can be given for pp hemorrhage? \

A

1st line= oxytocin

2nd line (continued bleeding) = Carboprost, Methylergonovine

28
Q

Carboprost, a med used for pp hemorrhage, what is a CI

A

Carboprost (prostaglandin analog) CI= asthma b/c causes bronchospasm

29
Q

What is diagnostic of IUP?

A

Yolk sac w/in gestational sac

intrauterine fetal pole, or intrauterine fetal heart activity

30
Q

What is the most frequently encountered cystic structures in normal ovaries.

A

follicular cysts

31
Q

most ovarian enlargements (75%) are caused by what?

A

functional ovarian cysts

32
Q

What is a congenital risk factor for cervical insufficiency

A

Ehler’s Danlos