Gustation and Olfaction Flashcards

1
Q

What are the 6 tastes?

A

Salt, sweet, fat, umami, sour, bitter

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2
Q

______ are taste sensitive structures

A

papillae

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3
Q

Basolateral surface is outside/inside of the taste buds, andd its where communication to NS happens

A

inside

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4
Q

How many types of taste cells in a single taste bud?

A

3

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5
Q

Salts detect sodium ions, causing taste cells to depolarise through which channels?

A

amiloride sensitive Na channels

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6
Q

Sensory transduction of sour tastes involves intracellular acidification, leading to a block in which channels?

A

potassium channels in membranes

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7
Q

T/F- Voltage gated channels respond to salty tastes

A

False- they dont

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8
Q
Sensory transduction of sweet and umami tastes include heterodimer G protein receptors. Sweet taste contains \_\_\_\_\_\_ receptors whereas umami receptors contain \_\_\_\_\_\_\_ receptors.
A) T1R2/T1R3, T1R1/T1R3
B) T1R2/T1R1, T1R1/T1R3
C) T1R2/T1R3, T1R2/T1R3
D) T1R2/T1R1, T1R1/T1R2
A

A) T1R2/T1R3, T1R1/T1R3

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9
Q

In sensory transduction of sweet and umami tastes, receptors couple to phospholipase C modulate _____, leading to release of _____.

A) Na, K
B) K, na
C) K, Ca
D) Na, Ca

A

C) K,Ca

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10
Q

T1R1/T1R3 receptors respond to _____, and are enhanced by _____.

A) glutamate, inosine
B) GABA, inosine
C) glutamate, diosine
D) GABA, diosine

A

A)

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11
Q

Depolarisation of taste cells leads to the release of excitatory transmitters that depolarise gustatory afferent terminals. ATP is one of those. What does it do?

A

activates ionotropic receptors on terminal membrane of gustatory axons

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12
Q

Gustatory afferents synapse at ______, part of the _____. It then projects to _______

A

gustatory nucleus, solitary nuclues of medulla, ventral posterior medial nuclueus of thalamus

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13
Q

Olfactory epithelium is located where?

A

Roof of nasal cavity

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14
Q

Olfactory receptors cells sends axons through ____ to the ______

A

Cribiform plate, olfactory bulb

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15
Q

T/F- Each olfactory receptor cell expresses a different receptor protein,

A

Trueq

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16
Q

Describe the process of olfactory transduction

A

Odorant molecule–> odorant receptor molecule–> activates adenyl cyclase–> in conjuction with ATP, activates cAMP—> influx of Ca and Na–> Ca pushes Cl out–> membrane depolarisation

17
Q

What is the order of the structure of the olfactory bulb?

A

Olfactory receptor cells-> axons of olfactory receptor cell-> Glomerulus-> Peri glomerular cells–> Tuftel cell–> Mitral cell–> then to olfactory cortex

18
Q

T/F- Receptor cells that synapse on a particular glomerulus all have different receptor fields

A

false- express same receptor field

19
Q

T/F- Indiivdual glomeruli encode only one odour, and granule cell neuron act as tuning interneuron.

A

True

20
Q

Briefly describe the central olfactory pathway

A

Olfactory receptor–> (via olfactory nerve) Olfactory bulb–> (via olfactory tract) olfactory targetsr

21
Q

T/F- olfactory receptor cells goes through cortex first and then the thalamus

A

True