Guillain-Barre Flashcards
1
Q
what is gbs
A
autoimmune disorder
myelin sheath damaged by autoantibodies
2
Q
onset of GBS
A
days to weeks following a viral infection
3
Q
possible etiologies/triggers of GBS
A
viral infection
bacterial infection (campylobacter jejuni)
post surgery
4
Q
clinical manifestations of GBS
A
weakness/tingling in lower extremeties ascending or descending patterns severity of symptoms increase over hours or weeks uncoordinated movements numbness and decreased sensation loss of bowel/bladder control blurred vision difficulty breathing, swallowing and chewing
5
Q
when in GBS life threatening
A
when it effects the respiratory muscles
6
Q
GBS pharmacology
A
no known cure
steroid therapy
high dose immunoglobulin therapy to shorten the severity and duration
7
Q
what is the goal of pharm therapy in GBS
A
reduce severity and accelerate recovery
8
Q
prognosis of GBS
A
95% survival
73% complete recovery
25-50% residual weakness after 3 yrs
about 3% may suffer relapse of muscle weakness and tingling many years post initial attack
