Guidelines Flashcards

1
Q

When you reduce your LDL-C by 1%, how much do you reduce your CVD risk?

A

1%

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2
Q

What are the 4 groups of patients for statin therapy?

A
  1. Adults with clinical ASCVD w/o class II-IV HF or receiving hemodailysis. 2. Adults with LDL-C > 190 mg/dl
  2. Adults 40-75 y/o with diabetes 4. Adults with > 7.5% estimated 10-year risk of ASCVD
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3
Q

What is the 2013 LDL-C treatment goal for a 50 y/o white nonsmoker with 1 previous of MI?

A

THERE IS NONE I FOOLED YOU!

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4
Q

What optional additional risk measurement tools can help to refine predicted risk in pts with “intermediate risk”?

A
  1. Family history of premature ASCVD 2. hsCRP 3. Coronary artery calcium 4. Ankle brachial indices.
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5
Q

What are the ABCDE treatment recommendations?

A

A. Aspirin/Antiplatelet therapy B. BP control C. Cholesterol control/cigarette smoking cessation D. Diet and weight management/ diabetes control E. Exercise

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6
Q

Define premature heart disease.

A

< age 55 for men and <65 for women

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7
Q

Lifestyle recommendations for ALL patients regardless of risk

A

DASH - like diet, Physical activity, weight management, smoking cessation

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8
Q

Total Cholesterol goals

A

Optimal - 240

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9
Q

Tryglycerides goal

A

< 150 mg/dL

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10
Q

What is the treatmnet for high total cholesterol?

A

Total cholesterol is not a target for therapy.

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11
Q

What is the treatment for high triglycerides?

A

diet, exercise, weight loss, Fibrates, Niacin, Fish Oil.

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12
Q

HDL Goals

A

Low - 60

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13
Q

Treatment for low HDL

A

Exercise, Niacin, Fibrates

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14
Q

Pharmacotherapy for high LDL

A

Statins, niacin, ezetimibe, bile acid sequestrants

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15
Q

How often should a healthy adult get a fasting lipoprotein profile?

A

Every 5 years

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16
Q

Which statins should be used for primary prevention?

A

Pravastatin, lovastatin, atorvastatin, rosuvastatin

17
Q

Which statins should be used for secondary prevention?

A

Simvastatin, Pravastatin, Atorvastatin

18
Q

High intensity statin therapy

A

Atorvastatin 40-80mg; Rosuvastatin 20-40 mg

19
Q

Moderate -Intensity statin therapy

A

Atorvastatin 10-20, Rosuvastatin 5-10, Simvastatin 20-40, Pravastatin 40-80, Lovastatin 40, Fluvastatin XL 80, Fluvastatin 40 mg BID, Pitavastatin 2-4mg

20
Q

Low- intensity statin

A

Simvastatin 10, Pravastatin 10-20, Lovastatin 20, Fluvastatin 20-40, Pitavastatin 1 mg

21
Q

What is the primary goal of managing very high TG concentrations?

A

Prevent pancreatitis

22
Q

% statins lower TG

A

10-30

23
Q

% Fibrates lower TG

A

30-50

24
Q

% IR Niacin lowers TG

A

20-50

25
Q

% ER Niacin lowers TG

A

10-30

26
Q

% Ezetimibe lowers TG

A

5-10%

27
Q

% Omega-3 fatty acids lower TG

A

20-50