GU System Flashcards
Homeostatic functions of urinary system
- Regulating blood volume and pressure
- Regulating plasma concentrations of sodium, potassium, chloride, other ions
- Stabilizing blood pH
- Conserving nutrients
Nephron
Basic functional unit in the kidney and where urine production begins
Metabolic waste products
- Urea - Most abundant organic waste formed through breakdown of amino acids
- Creatinine - generated in skeletal muscle through breakdown of creatine phosphate
- Uric acid - breakdown of RNA molecules
Nephron process
- Filtration - blood pressure forces water across the filtration membrane
- Reabsorption - removal of water and solute molecules from tubular fluid
- Secretion - transport of solutes into tubular fluid
Glomeruler filtration rate (GFR)
Amount of filtrate produced by the kidney each minute
Function of the urinary system
- Maintain blood volume
- Balance of water, electrolytes, pH
- Ensures key elements remain in blood (eg., glucose)
- Waste removal
- Regulation of arterial BP
- Development of RBCs
Kidney failure
Loss of blood pressure and blood flow to kidneys
Testicular torsion
Twisting of spermatic cord
Loss of cremasteric reflex, horizontal lie, painful and swollen
Benign prostatic hypertrophy
Non-cancerous increase in size of prostate gland
Frequent urination, trouble starting to urinate, weak stream, inability to urinate, or loss of bladder control
Causes of non-traumatic GU issues
- Inflammatory/immune mediated disease
- Infectious disease
- Physical obstruction
- Hemorrhage
Acute renal failure
Sudden drop in urine production because kidneys suddenly unable to filter waste products from blood; dangerous amounts of waste accumulate in blood
Edema of feet, sudden drop in urine output
Caused by hypertension, chronic heart failure, diabetes, chronic infection, autoimmune disease
Diabetic nephropathy
Kidney damage due to diabetes that causes the filter to become leaky, letting protein into urine
Tests include CT scan, urine output measure, blood test, urine test, biopsy
Chronic renal failure
Inadequate kidney function due to permanent loss of nephrons (~70%)
End stage occurs when ~80% of nephrons lost
Causes metabolic instability and requires dialysis or transplant
ECG will show what type of waves if there is high potassium retention?
Peaked T-waves
Renal calculi
Kidney stones - crystal aggregation in kidney’s collection system
Pain in back, side, and groin, blood in urine, painful urination, abnormally coloured urine, fever, chills, diaphoresis, N/V
Nephrolithiasis are small hard mineral deposits that form inside kidneys