GU Flashcards

1
Q

What is stress incontinence?

A

Leakage of urine with activities causing increased intra-abdominal pressure (coughing, laughing, sneezing, etc.)

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2
Q

What are 2 diagnostic tests for stress incontinence?

A

Cough stress test (pos if urine leak w/cough)
Cotton swab test (pos if angle change is > 30*)

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3
Q

What is the treatment for stress incontinence?

A

Conservative: avoid excess fluids, scheduled voiding, pelvic floor rehab
Meds: non are FDA approved; can try phenylpropanolamine or duloxetine
Surgery: intravesicular balloon, sling procedure, urethropexy

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4
Q

What is urge incontinence?

A

Sudden urge to urinate w/subsequent leakage, leakage of urine prior to reaching toilet, or bladder contraction stimulated by senses (running water, cold weather, arriving home, etc.)

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5
Q

What is the treatment for urge incontinence?

A

Conservative: avoid excess fluid, scheduled voiding, pelvic floor rehab
Meds: Antimuscarinics (darifenacin or solifenacin, tolterodine or fesoterodine, oxybutynin) topical vaginal estrogen (mirabegron) (not FDA approved)
Surgery: neuromodulation, botox A injection

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6
Q

In terms of treatment, if someone presents with mixed incontinence, how do you treat it?

A

Focus on addressing the predominant symptoms

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7
Q

What is overflow incontinence?

A

Urinary dribbling, leakage of urine without preceding urge, weak urinary stream, sensation of incomplete bladder emptying

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8
Q

What diagnostic test can be performed for overflow incontinence?

A

Pelvic ultrasound w/post-void residual volume (pos if > 200mL remains in bladder)

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9
Q

What is the treatment for overflow incontinence?

A

Conservative: intermittent cath, indwelling cath
Meds: alpha-adrenergic antagonists (terazosin or tamsulosin)
Surgery: suprapubic cath

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10
Q

When does functional incontinence occur?

A

In pts with normal urinary tracts, but have cognitive or physical barriers to toileting (dementia, severe depression, physical disability, etc.)

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11
Q

What is enuresis?

A

Incontinence while sleeping after the age that bedwetting is common (> 7 yo)

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12
Q

What is the treatment for enuresis?

A

Avoid caffeine later in the evening
Avoid fluids just before bed
Bed moisture alarms

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13
Q

What is the most common formulation of nephrolithiasis (kidney stone)?

A

Calcium oxalate

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14
Q

What are signs/symptoms of nephrolithiasis?

A

Stone in kidney: asymptomatic
Stone in ureter: restlessness, frequent/painful urination, flank pain that radiates to groin on affected side, hematuria

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15
Q

What is the test of choice for nephrolithiasis if the pt has hematuria?

A

Renal CT without contrast

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16
Q

What is the treatment for nephrolithiasis?

A

Pain management (NSAIDs or opioids)
Increase fluid intake
Dilation of ureters w/tamsulosin (flomax) (take before bed)

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17
Q

When would nephrolithiasis require surgery/admission to the hospital?

A

Surgery: stone is > 6mm or delayed passage (nephrolithotomy, rigid & flexible ureteroscopy, shockwave lithotripsy)
Admit: obstructed/infected upper urinary tract, intractable vomiting or pain, anuria or deteriorating renal function, hx of kidney transplant/solitary kidney w/obstructing stone

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18
Q

What are the formulations of stones based on urine pH level?

A

pH > 8: calcium and phosphate
pH < 6: uric acid or crystine

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19
Q

What size of a kidney stone is likely to pass on its on, and when should you refer to urology?

A

< 4mm will pass on its own
Refer to urology if stone is > 6mm or stone is < 6mm but has not passed in 4 weeks

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20
Q

Where in the urinary tract are stones more/less likely to pass from?

A

Proximal ureter: less likely to pass
Distal ureter: more likely to pass

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21
Q

What causes 90% of acute bacterial prostatitis?

A

E. coli

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22
Q

What are signs/symptoms of acute bacterial prostatitis?

A

Fever/chills
Fatigue
Myalgias
Dysuria
Urinary frequency
Urinary hesitancy
Suprapubic/pelvic/perineum pain
Recent hx of UTI, prostate biopsy, prostate manipulation

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23
Q

What test should be performed when working up a pt for acute bacterial prostatitis who is < or = to 35 yo or has high-risk sexual activity?

A

Gonorrhea/chlamydia

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24
Q

What is the treatment for acute bacterial prostatitis?

A

Mild-mod: Bactrim or Cipro x 6 weeks
Severe: Ampicillin 2g IV q6 hrs + Gentamicin 5mg/kg QD until afebrile, once afebrile/stable Bactrim or Cipro x 6 weeks

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25
What med that is used for acute bacterial prostatitis should you not give if the pt has an underlying arrhythmia?
Cipro
26
What test SHOULD NOT be performed in suspected acute bacterial prostatitis?
Prostate massage (could induce sepsis)
27
How is chronic bacterial prostatitis different from acute bacterial prostatitis?
Chronic: lasts > 3 months with urine culture showing same bacterial species Sx: no fever, no myalgias/fatigue
28
What is the preferred and alternative test for chronic bacterial prostatitis?
Preferred: 4 glass pre/post-prostatic massage test Alternative: 2 glass pre/post prostatic massage test
29
What is the preferred treatment for chronic bacterial prostatitis?
Cipro 500mg BID OR Levofloxacin 500mg QD x 6 weeks
30
What is the 1st line treatment for pts w/chronic prostate/pelvic pain syndrome (prostate/pelvic pain > 3 months with negative workup)?
Bactrim or Cipro x 6 weeks
31
What is a nonmalignant growth of prostate tissue?
Benign prostatic hyperplasia
32
What are the signs/symptoms of benign prostatic hyperplasia?
Urinary hesitancy Stream weakness or dribbling Prolonged time to empty urine Sensation of incomplete bladder emptying Nocturia
33
What diagnostic tests may be ordered for benign prostatic hyperplasia?
Prostate specific antigen (PSA) Cystoscopy Post-void residual volume
34
What is the treatment for benign prostatic hyperplasia?
Early/intermittent symptoms: watchful waiting & lifestyle changes Regularly symptomatic: alpha blockers (tamsulosin), alpha reductase inhibitors (finasteride) or antimuscarinics (solifenacin, oxybutynin) Advanced disease: surgery via transurethral resection prostatectomy (TURP), holmium laser enucleation of the prostate (HoLEP) or urolift
35
What is the normal size of a prostate?
Size of a walnut (3 cm)
36
What is the most common urinary tract neoplasm?
Bladder cancer
37
What are signs/symptoms of bladder cancer?
Pelvic or lower back pain Persistent microscopic hematuria Gross hematuria Feeling of constant menstrual cramping
38
What is the gold standard diagnostic test for bladder cancer?
Cystoscopy with biopsy
39
What procedure is performed when treating bladder cancer?
Transurethral resection of bladder tumors (TURBT) (for non-muscle invasive tumors)
40
What is the most common therapy for treatment of bladder cancer?
BCG (immunotherapy derived from strain of bacteria)
41
Is there currently any screening done for bladder cancer?
No
42
What is the most diagnosed malignancy worldwide and the 5th leading cause of cancer death in men?
Prostate cancer
43
What are the signs/symptoms of prostate cancer?
Frequent urination Nocturia Stream weakness Gross hematuria Dysuria Difficulty achieving erection Painful ejaculation Firm/hard/asymmetric prostate nodule on PE
44
What is the gold standard diagnostic test for prostate cancer?
Prostate biopsy
45
What test is used to screen men aged 55 to 70 for prostate cancer?
Prostate specific antigen (PSA)
46
What is the treatment for prostate cancer?
Low grade: annual PSA, 1 additional biopsy 12-18 months later Low-intermediate w/o mets & > 10 yr life expectancy: surgical excision/prostatectomy, radiation, hormone therapy High grade: prostatectomy, radiation, chemo hormone & immunotherapy With mets: no curative treatment
47
What system is used to grade tissue from a prostate biopsy?
Gleason Scoring System
48
What side effects should pts be warned about when being treated for prostate cancer?
Erectile dysfunction Urinary incontinence Loss of libido Loss of bone density
49
What is the most common malignancy in men aged 15-45?
Testicular cancer
50
What are signs/symptoms of testicular cancer?
Lower abd/pelvic pain Unilateral testicular mass Painless scrotal swelling
51
What is the treatment for testicular cancer?
Radical inguinal orchiectomy (side w/mass) Chemo Radiotherapy
52
What pts can have an uncomplicated UTI (cystitis/lower UTI)?
Pts w/female organs w/no structural abnormality, no diabetes, are < 65 yo, are not pregnant, and are not immunocompromised
53
What are the signs/symptoms of cystitis/lower UTI?
Dysuria Urinary frequency/urgency Suprapubic discomfort or fullness Cloud urine AMS (in elderly)
54
What pts get treated for a UTI even if they are asymptomatic?
Pregnant pts Amoxicillin or Cephalexin (Keflex) x 3-7 days
55
What is the treatment for uncomplicated UTI?
Bactrim OR Keflex (1st line in Roanoke) OR Macrobid x 3-7 days
56
What types of pts/symptoms are considered a complicated UTI?
Uncomplicated characteristics & 1 or more of the following: Symptoms lasting > 7 days Symptoms in the upper urinary tract Pt w/male organs
57
What is the treatment for complicated UTI?
Mild-mod: Cipro or Bactrim x 5-14 days Severe: admission with IV ceftriaxone, levofloxacin, or bactrim
58
What meds used to treat UTI should be cautioned/not used in pregnancy?
Bactrim cannot be used after 3rd trimester Levofloxacin cannot be used at all
59
What is different in pyelonephritis than a UTI?
Infection is in the upper urinary tract May have CVA tenderness on PE
60
What is the treatment for pyelonephritis?
Uncomplicated: Cipro or Bactrim x 5-14 days Complicated: admit w/IV ceftriaxone, levofloxacin, gentamicin, or bactrim
61
How is recurrent UTI defined?
Greater than 2 infections in 6 months OR 3 infections in 1 year
62
What is the treatment for recurrent UTI?
Education on hygiene Vitamin C supplementation Prophylactic post-coital abx (nitrofurantoin) Estrogen vaginal cream 2x/week (for postmenopausal women)
63
What is 1st line treatments for erectile dysfunction?
Lifestyle/behavioral mods 1st line meds: Sildenafil (viagra) Tadalafil (Cialis)
64
What is the gold standard treatment for premature ejaculation?
Behavioral therapy
65
What are signs/symptoms of balanitis?
Penile discharge Pain/difficulty retracting foreskin Itching Tenderness Difficulty urinating Inflammation of glans
66
What is the treatment for balanitis?
Clean it Topical antifungals if candida suspected
67
What is Peyronie's disease?
Painful/curved penis during erection
68
What is the treatment for Peyronie's disease?
Surgical fixation
69
What is priapism?
Persistent (> 4 hrs), painful erection
70
What diagnostic test is used when working up priapism?
Dopper ultrasound
71
What is the treatment for priapism?
Consult urology Terbutaline (PO or sub q) Corporal aspiration & saline irrigation Intracavernosal injection Urological surgical intervention
72
What pt demographic is most common to see testicular torsion?
Males < 30 yo
73
What are the signs/symptoms of testicular torsion?
Acute onset of severe pain that is constant N/V Scrotal swelling High position of testes Abnormal cremasteric reflex
74
What is the treatment for testicular torsion?
Attempt de-torsion Surgery