Growth And Ax In Children-adolescents

Question 1

2 types of growth restriction

Answer 1

Failure to thrive: underlying nutrition or chronic disease

Short stature - endocrine

Question 2

When document height and weight in kids?

Answer 2

EVERYTIME!!

Question 3

Why glucocorticoids bad for growth?

Answer 3

Inhibit chondroblastic maturation

Question 4

How to get expected height?

Answer 4

Height of parents and subtract 6.5 girls and add 6.5cm for boys

Question 5

Growth hormone mechanism

Answer 5

GH>GH receptor>IGF-1>Bone>growth

Question 6

New born screening

Answer 6

Cystic fibrosis

PKU

Question 7

Overweight is?

Answer 7

85%-95%

Question 8

Failure to thrive is?

Question 9

Obese is what centile?

Answer 9

> 95th %

Question 10

What is the major contributor to growth spurt in puberty?

Answer 10

Estrogen.

Question 11

Determinants of skeletal bone age delayed?

Answer 11

Hypothyroidism, glucocorticoid excess, growth hormone deficiency, chronic disease

Question 12

What causes bone age acceleration

Answer 12

Obesity,
early puberty
Hyperthyroidism
Androgen excess

Question 13

Nutritional causes of growth failure? 3

Answer 13

Undernutrition
Micronutrient deficiencies - iron, Vit D
Gut malabsorption - Coeliac, CF, Crohn’s

Question 14

When does growth hormone secrete during 24 hour period?

Answer 14

At night

Question 15

Endocrine causes of short stature?

Answer 15

Hypothyroidism (autoimmune)
GH deficiency
Glucocorticoid excess (GP: if asthma every 4-6 weeks)

Question 16

What do kids with endocrine causes of short stature kids look like BMI wise?

Answer 16

Normal or overweight BMI

Question 17

Why cushing’s get muscle mass loss?

Answer 17

Get proteinolysis of muscles

Flat-lining of linear growth

Question 18

Growth with obesity is?

Answer 18

Accelerated