Growing Flashcards
1
Q
How do we measure growth?
A
- Weight
- Height/length
- Head circumference
2
Q
What is the significance of growth charts
A
- A method of describing the growth of a normal population- the reference population
- A way of comparing the growth of an individual with the reference population
- A tool helping to define abnormal growth of an individual
3
Q
How do we construct growth charts
A
- Define the reference population
- A mathematical construct
- Longitudinal or cross-section
- Centiles
4
Q
What are the 3 phases of growth & their requirements?
A
- ) Infancy
- nutrition
- insulin - )Mid-childhood
- Growth hormone
- thyroxine - ) Puberty
- GH
- sex hormone
5
Q
Define anthropometry
A
The scientific study of the measurements and proportions of the human body.
6
Q
What is Laron’s syndrome
A
- May cause short stature
- GH insensitivity
7
Q
What are some signs of coeliac disease
A
- Tiredness
- Anaemia
- Positive antibodies
- Positive jejunal biopsy
- Response to diet
8
Q
List some first line investigations for abnormal growth
A
- FBC
- Ferritin
- U&E (kidney function)
- CRP/ESR
- TFT
- Coeliac screen
- IGF-1
- Bone age
- CGH array/karyotype
9
Q
How do we obtain subischial leg length?
A
-Subtract sitting height from standing height
10
Q
List some second line investigations for abnormal growth
A
- GH provocation test ( stress people to produce it) +/- additional pituitary function tests
- MRI brain
- Skeletal survey
11
Q
Which conditions has treatment with GH been licensed for ?
A
- GH deficiency
- Turner’s syndrome
- Prader Willi syndrome
- SHOX deficiency
- Chronic renal failure
- SGA& poor catch up
