Group Presentations

Question 1

What is Systemic Lupus Erythematosus?

Answer 1

Autoimmune disease where Body’s immune system mistakenly attacks healthy tissue

Question 2

What is going on with the lymphocytes in people with lupus?

Answer 2

B Cells produce antibodies which target self

Treg Cells are low in number and function impaired

Question 3

What is Guillain-Barré syndrome?

Answer 3

Autoimmune disease where the body’s immune system attacks the peripheral nervous system

Question 4

What is going on immunologically with Guillain-Barré syndrome?

Answer 4

Antibodies are attacking the axons of the peripheral nervous system

Question 5

What is Type 1 Diabetes?

Answer 5

Autoimmune disease where T Cells target/kill Beta cells in the pancreas so insulin can’t be produced

Question 6

What is Grave’s Disease?

Answer 6

Autoimmune disorder that ultimately causes

Hyperthyroidism

Question 7

What is a pollen allergy?

Answer 7

A Type I Hypersensitivity, where immune system reacts to non-self/non-harmful pollen antigens.

Question 8

What is the primary and secondary pollen allergic response?

Answer 8

● Primary response:
○ B cell release IgE antibody
● Secondary response:
○ Mast and basophil cells release histamine

Question 9

What is Lyme Disease?

Answer 9

Disease transmitted by bacteria Borrellia borgdorferi. Causes neurologic and cardiac complications.

Question 10

What are Xenografts?

Answer 10

transplant of any live cells, tissues, or

organs from a nonhuman animal source to a human recipient

Question 11

What Three major factors determine whether a donor and a recipient are compatible?

Answer 11

blood type, tissue type, and cross-matching.

Question 12

What is ADA deficiency?

Answer 12

Adenosine deaminase (ADA) deficiency Autosomal metabolic disorder that causes severe combined immunodeficiency (SCID)

Question 13

What is the effect of ADA deficiency?

Answer 13

People affected with ADA deficiency lack almost all immune protection from bacteria, viruses, and fungi

Over time, it can cause chronic lung damage and malnutrition

Question 14

What is leukemia?

Answer 14

Type of blood cancer found in your blood and bone marrow and is caused by the rapid production of abnormal white blood cells

Question 15

What are the types of leukemia?

Answer 15

• Acute lymphocytic leukemia (ALL)
• Acute myelogenous leukemia (AML)
• Chronic lymphocytic leukemia (CLL)
• Chronic myelogenous leukemia (CML)

Question 16

What are peanut allergies?

Answer 16

Type I Hypersensitivity caused by peanuts (legumes)

Question 17

What does radiation do to cancer?

Answer 17

Kills cancer cells and enhances T and NK cell therapies.

Creates abscopal effect.

Question 18

What is Multiple sclerosis?

Answer 18

autoimmune disease primarily driven by T cells working against components of the myelin sheath in the CNS.

Question 19

What is going on immunologically with multiple sclerosis?

Answer 19

CD4 T cells become activated and cross the blood-brain barrier

Destruction of oligodendrocytes with demyelination of axons

Question 20

What is Berger’s Disease/IgA Nephropathy?

Answer 20

Autoimmune disorder that results in the Deposition of IgA in glomeruli of kidneys

Question 21

What are the requirements for a hand transplant?

Answer 21

matching blood type, skin tone, gender, and size