graves/hashimotos/diabetes insipidus/pituitary hypofunction Flashcards
antibodies bind to surface of thyroid follicular cells, cause stimulus similar to TSH
graves disease
cause hypersecretion of T3/T4
graves disease
IgG antibodies cause destruction of gland
hashimotos
painless, diffuse enlargement of thyroid
mononuclear infiltration (lymphocytes and plasma cells)
healing and fibrosis and reduce size of thyroid
hashimotos
most pts have exopthalmos
graves disease
contains lymphoid follices
graves disease
High T3/T4 and low TSH
graves disease
Low T3/T4 and high TSH
hashimotos
synthetic thyroid hormones
hashimotos
antithyroid drugs if ineffective, thyroidectomy
graves disease
hyperactive tall cuboidal cells
enlarged thyroid
graves disease
what are S&S of adult panhypopituitarism
general weakness cold intolerance poor appetite weight loss hypotension
increased risk of B-Cell lymphomas
hashimotos
symptoms associated with nodular goiter
coughing and hoarseness
MC cause of enlarged thyroid
idiopathic
hypothyroidism in children causes what
dwarfism (affects body growth)
cretinism (mental development retarded)
adult hypothyroidism S&S
heart beats slowly
constipation
skeletal muscles weak, stiff, ache
what does myxedema look like in hypothyroiditis
pt appears edematous, dough-like and puffy
major symptoms of diabetes insipidus
polyuria
nocturia
polydipsia
compression of pituitary stalk by tumor
hypo release of ADH
excess release of low osmol urine
diabetes insipidus
what is a carniopharyngiomas
benign tumor arise from pituitary
easily removed
does not produce hormones
big enough to cause hypofunction of pituitary
