GRAT Heart Failure Drugs

Question 1

2 diuretics and their mode of action

Answer 1

furosemide and metolazone

Question 2

side effects of diuretics

Answer 2

hypotension, neurohumoral activation, electrolyte abnormalities, renal dysfunction

Question 3

what drugs help with systemic congestion

Answer 3

diuretics

Question 4

2 nitrates and their mode of action

Answer 4

GTN and SNP

venodilation, arterial vasodilation

Question 5

side effects of nitrates

Answer 5

profound hypotension with vasodilators, dec coronary perfusion (SNP)
headache, metabolite toxicity

Question 6

what drugs have a therapeutic goal of vasodilation

Answer 6

nitrates

Question 7

2 examples of inotropes and their mode of action

Answer 7

B agonists, PDE-3 inhibitors, levosimendan

inc force of myocardial contraction and peripheral vasodilation (inodilation)

Question 8

side effects of inotropes

Answer 8

inc myocardial oxygen demand, hypotension, arrhythmias

Question 9

what drugs have a therapeutic goal of cardiac function

Answer 9

inotropes

Question 10

3 beta blockers and their mode of action

Answer 10

esmolol, metoprolol, digoxin

reduce HR and sympathetic activity; antiarrhythmic

Question 11

side effects of beta blockers

Answer 11

bradycardia, hypotension

Question 12

drugs whose therapeutic goal is cardiac stability

Answer 12

beta blockers