Exam 2 other info Flashcards
atrophy
dec muscle mass, dec myofibril protein mass, dec MHC content
loss of force and power
vascular regression
functional and structural alterations in hemodynamics
consequences of atrophy
dec protein synthesis loss of regulatory and contractile protein loss not equal with other proteins exposes muscle to damage inc fatigability dec capacity for lipid oxidation
concentric hypertrophy
pressure overload
inc wall thickness
dec chamber size
eccentric hypertrophy
volume overload
dec wall thickness
inc chamber size
hypertrophy
inc in SIZE of cells
poiseuille’s law
Q is proportional to nXL / r^4
ratio of driving pressure to blood flow is a function of resistance
motion of blood through a tube depends on P and length and radius of the tube and blood viscosity
- it opposes its flow to an extent determined by its dimensions
3 layers of arteries/veins
intimal layer (innermost) elastic layer (medial) adventitial layer (outer layer)
resistance in arteriole - SVR
smooth muscle function acting as sphincter - high resistance ring
can contract to make the hole smaller or relax to make it bigger
difference in volume between veins and arteries
same change in P but get a bigger change in volume in veins than in arteries
linear flow of blood - arteries to veins
artery, arterioles, capillaries, venules, veins
BP in linear flow
BP high until it hits capillaries, slows down, stays low in veins
Velocity in linear flow
highest in arteries, drops to almost nothing in capillares, rises not as high but high in veins
total area in linear blood flow
highest in capillaries
hematocrit
the volume of whole blood that is cells, mostly RBC
% RBC in blood
index of blood viscosity
inc in hematocrit inc RBC %
