Granulomatosis with polyangitis (GPA) Flashcards
1
Q
what is GPA?
A
an autoimmune granulomatous vasculitis associated with raised plasma c-ANCA antibody
2
Q
symptoms of GPA
A
a triad of midline respiratory involvement (nasal bridge collapse) haemoptysis and renal impairment
3
Q
treatment of GPA
A
combined regime of cyclophosphamide and high dose steroids
rituximab for second line