Granulomatosis with polyangitis (GPA) Flashcards

1
Q

what is GPA?

A

an autoimmune granulomatous vasculitis associated with raised plasma c-ANCA antibody

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2
Q

symptoms of GPA

A

a triad of midline respiratory involvement (nasal bridge collapse) haemoptysis and renal impairment

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3
Q

treatment of GPA

A

combined regime of cyclophosphamide and high dose steroids

rituximab for second line

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