Granulocyte Qualitative disorders Flashcards

1
Q
  • recurrent soft tissue infections
  • delayed separation of umbilical cord
  • poor wound healing
  • neutrophilia
A

LAD

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2
Q

LAD defect

A
  • partial deficiency of CD18
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3
Q
  • neutrophilia

- Catalse positive infections

A

CGD

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4
Q

Defect in CGD

A
  • defect in oxidase enzyme system
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5
Q
  • oculocutaneous albinism
  • neutropenia
  • neurodegenerative disease
  • formation of giant, leaky granules
A

Chediak Higashi syndrome

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6
Q
  • generally healthy
  • Increased fungal infection with diabetes
  • Can’t kill Candida
A

MPO deficiency

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7
Q

Deficiency in factors 1q, 4, and 2

A

SLE and other autoimmune

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8
Q

C3 deficiency

A

H influenza

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9
Q

Defects in components C5-C9

A

Neisseria infections

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