Gram Positives Flashcards

1
Q

what are the gram positives coccus

A

staphylococci
streptococci
enterococci

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2
Q

what are the gram positive bacilli

A

listeria monocytogenes
clostridia (c.diff)
corynebacterium

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3
Q

what are some beta lactic antibiotics other than penicillin

A
flucloxacillin 
amoxicillin 
cephalosporins 
pepercillin/tazobactam 
carbepenems
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4
Q

what part of the penicillin structure makes people allergic

A

beta lactam ring

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5
Q

why do you give beta lactic drugs multiple times a day

A

because a lot of drug is needed to kill the bug

the MIC is high

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6
Q

what is the MIC of a drug

A

minimum inhibitory concentration

this is the minimum concentration of the drug needed to kill 99.9% of bugs during 18 to 24 hours

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7
Q

do you give IV or oral antibiotics in sepsis

A

always IV unless it is c.diff then oral

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8
Q

how often is gentamicin given

A

once a day because it causes receptors to be saturated but not toxicity?

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9
Q

what is beta haemolysis

A

complete lysis and clear zone seen on blood agar

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10
Q

what is alpha haemolysis

A

partial haemolysis giving a greenish tinge

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11
Q

what is gamma haemolysis

A

non-haemolytic

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12
Q

how do lance field groups categorise antibiotics

A

by their cell wall carbohydrates

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13
Q

what group is strep progenies

A

group A beta haemolytic strep

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14
Q

where does strep pyroxenes cause infection

A

skin, pharyngitis

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15
Q

what is group b haemolytic strep otherwise known as

A

streptococcus agalactaiae

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16
Q

where does strep agalactaiae cause infection

A

pregnancy and neonates

17
Q

what is strep viridian’s

A

a group of many different organisms

18
Q

what infections does strep pneumoniae cause

A

otitis media
pneumonia
meningitis

19
Q

what is the antibiotic of choice for strep pneumoniae

A

penicillin (unless you have travelled in last 6 months)

20
Q

where do enterococci live

A

large bowel

21
Q

what is the most common enetococci

A

enterococci faecalis

22
Q

what are the 2 types of enterococci

A

e. faecalis

e. faecium

23
Q

what is the antibiotic of choice for enterococci

A

amoxicillin

vancomycin - 2nd line

24
Q

what antibiotic only covers gram positives

A

vancomycin

25
Q

antibiotic of choice for staph aureus

A

flucloxacillin

give vancomycin if they’re actually allergic in sepsis

26
Q

staph aureus is coagulase negative true/false

A

false

coagulase positive

27
Q

name a coagulase negative staph

A

staph epidermidids

28
Q

what are the 3 gram positive bacilli you should know about

A

bacillus cirrus
listeria
c.dif

29
Q

treatment for c.dif

A

oral vancomycin

30
Q

what does listeria infection causes

A

gastroenteritis

31
Q

where can you get bacillus cerrus from

A

reheated rice

32
Q

what are the 4 C antibiotics which cause c.dif

A

clindamycin
co-amoxyclav
cepholasporin
ciprofloxin