Gram Positive Bacteria (Clostridium)

Question 1

Clostridium shape?

Answer 1

Rods

Question 2

2 facts about clostridium

Answer 2

Anerobic and spore producer

Question 3

Why is it advantageous to be a spore producer?

Answer 3

Allows baterium to survive adverse conditions such as temp, radiation,chemicals, and air exposure.
When conditions are favourable again bacteria will germinate.

Question 4

Clostridium causes which two infections?

Answer 4

Clostridium perfringens and clostridium difficile.

Question 5

What does Clostridium perfringen result in?

Answer 5

GAS gangrene

Question 6

What is GAS gangrene?

Answer 6

Localised death and decomposition of body tissue

Question 7

GAS gangrene / clostridium perfringen symptoms

Answer 7

Foul discharge and pain

Question 8

Clostridium perfringens / GAS gangrene treatments

Answer 8

Debridement essential

Question 9

Antibiotic associated diarrhoea AKA

Answer 9

Clostridium difficile

Question 10

C. diff gut commensal

Answer 10

3% adults, 75% infants

Question 11

C. diff can cause what? (2x)

Answer 11

Pseudomembrannous coliitis and toxic megacolon

Question 12

Who has is most likely to suffer from c.diff

Answer 12

over 65’s (80%) and people who take lots of abx

Question 13

SIGHT?

Answer 13

Suspect, isolate, gloves & apron, hand washing and test

Question 14

what is toxic mega colon?

Answer 14

Toxic dilation of colon

Question 15

What abx increase the risk of C.diff?

Answer 15

Cephalosporins, clindamycin and ciprofloxacin.

Question 16

How many deaths because of C.diff in 2011?

Answer 16

2,053

Question 17

How many hospital deaths ue to c.diff in 09-11

Answer 17

1%

Question 18

Treatment for c.diff?

Answer 18

Metronidazole