Gram negative bacilli (non-enterics) Flashcards
Haemophilus influenza Morphology/Structure
Gram negative
coccobacillus, facultative
anaerobe
Haemophilus influenza Virulence Factors
b polysaccharide
capsule, adhesion
proteins
Haemophilus influenza Diseases/Symptoms
Acute bacterial meningitis,
Symptoms include: fever,
stiff neck, vomiting,
neurological impairment
Haemophilus influenza Diagnostics
H. influenzae
cultured from
usually sterile
sites (e.g.,
cerebrospinal
fluid)
Haemophilus influenza Prevention/Treatment
Vaccine (Hib)
vaccine is against
b polysaccharide
capsule.
Amoxicillin and
cephalosporin.
Haemophilus influenza Immune Response
Can be part of
normal flora that
crosses bloodbrain barrier
Haemophilus influenza Modes of Transmission
Upper respiratory
tract of humans
form that has
capsule is
pathogenic
Pseudomonas
aeruginosa Morphology/structure
Gram negative rod, flagella,
aerobic
Pseudomonas
aeruginosa Modes of Transmission
Many people can
be asymptomatic
carrier, People in
hospitals,
swimming pools,
moist environments
Pseudomonas
aeruginosa Virulence Factors
Exotoxins, biofilms,
pyocyanin kills nasal
cilia, pyoverdin steals
host iron
Pseudomonas
aeruginosa Diseases/symptoms
UTI, bed sores,
Opportunistic and
nosocomial of
immunocompromised.
Can also lead to jacuzzi
rash (usually self limiting)
Pseudomonas
aeruginosa Diagnostics
Mac Conkey
agar - nonlactose
fermentor.
Oxidase positive,
rotting fruit odor
Pseudomonas
aeruginosa Prevention/Treatment
Multi drug
resistant.
Aminoglycosides
and
cephalosporins
have been known
to be effective,
some strains need
to use Imipenem
Pseudomonas
aeruginosa Immune Response
Opportunistic,
nosocomial
pathogen of
immunocompromi
sed. Also, people
with cystic
fibrosis can live in
excess mucus
and cause death.
Bordetella pertussis Morphology/structure
Gram negative, Coccobacillus, aerobic
Bordetella pertussis Modes of Transmission
Not normal flora of
human respiratory
tract, true
pathogen
Bordetella pertussis Virulence Factors
Capsule, Pertussis
toxin
Bordetella pertussis Diseases/Symptoms
Whooping Cough; mostly in
children, symptoms inc
lude: runny nose,
sneezing, fever, dry cough
makes whooping sound
Bordetella pertussis Diagnostics
Gram negative,
cocobacili,
diplococci
arrangement on
gram stain.
Cephalosporin
sensitive
Bordetella pertussis Prevention/Treatment
Cephalosporin,
Azithromycin,
Vaccine DTP or
DTPH
Bordetella pertussis Immune Response
Infants younger
than 12 months
have highest risk
for severe or life
threatening
conditions
