gram - DOC

Question 1

neisseria gonorrhoeae

• gonorrhea
• gonococcal pharyngitis

Answer 1

ceftriaxone (if gonorrhea also give azithromycin for chlamydia)

second line: azithromycin

Question 2

neisseria meningitidis

• meningitis
• bacteremia

Answer 2

ceftriazone

second line: chloramphenicol

Question 3

moraxella cattharalis

-otitis media

Answer 3

amoxicillin

macrolide if penicillin allergy

Question 4

Klebsiella pneumoniae

• pneumonia
• bacteremia

Answer 4

cephalosporin +/- aminoglycosides

second line: aztreonam and quinolones

Question 5

ETEC

Answer 5

ciprofloxacin (if warranted)

Question 6

EHEC

Answer 6

CI

Question 7

HUS from EHEC

Answer 7

eculizumab

Question 8

EIEC

Answer 8

floroquinolone (if warranted)

Question 9

E coli

-meningitis

Answer 9

3rd gen cephalosporin (ceftriaxone)

Question 10

E. coli

-pneumonia

Answer 10

3rd gen cephalosporin (ceftriaxone)

or floroquinolone

Question 11

E. coli

-UTI

Answer 11

fluoroquinolone, TMP-SMX or nitrofuratoin

Question 12

shigella

-bloody colitis

Answer 12

floroquinolone (if warranted)

3rd gen cephalosporin if cipro resistance

Question 13

salmonella

• nontyphoidal
• typhoidal

Answer 13

floroquinilone for both

nontyphoidal: pregnant pt and kids: ceftriaxone
typhoidal: ceftriaxone…. and kids: azithromycin.. chloramphenicol for resistance

Question 14

pseudomonas

-endocarditis, bacteremia

Answer 14

aminoglycoside + antipseudomonal b-lactams

azithromycin if allergy

Question 15

pseudomonas

-meningitis

Answer 15

ceftazidime

Question 16

pseudomonas

-osteomyelitis

Answer 16

beta-lactam, carbapenem or floroquinolone

Question 17

pseudomonas

-UTI

Answer 17

aminoglycoside or floroquinolone

Question 18

pseudomonas

-pneumonia

Answer 18

Antipseudomonal beta-lactam+ antipseudomonal quinolone (ciprofloxacinand levofloxacin)

Antipseudomonal beta-lactam + aminoglycoside

Antipseudomonal quinolone + aminoglycoside

Question 19

vibros

• cholera
• parahaemolyticus

Answer 19

fluids and electrolytes

Question 20

campylobacter

-bloody diarrhea

Answer 20

fluoroquinolone
or
azithromycin

Question 21

H. pylori

-gastric ulcer

Answer 21

PPI + amoxicillin + clarithromycin

Question 22

yersinia pestis

-plague

Answer 22

streptomycin (gentamicin)

second line: doxy, chloramphenicol

Question 23

bordetella pertussis

-pertussis

Answer 23

macrolide (historically erythromycin)

second line: TMP-SMX

Question 24

pasteurella multocida

-cellulitis

Answer 24

amoxicillin-clavulanate

second line: penicillin, doxy, floroquinolones

Question 25

francisella tularensis

-tularemia

Answer 25

stretomycin (gentamicin)

second line: cipro, doxy (for non-severe diseases)

Question 26

legionella pneumophilia

• legionnaires disease
• transplant pts

Answer 26

levofloxacin for both

légionnaires disease: azithromycin

Question 27

Brucella spp

-brucellosis

Answer 27

doxy + streptomycin

second line: doxy + rifampin

Question 28

bacteroides

-intraabdominal abscess

Answer 28

metronidazole

Question 29

HAECK

-endocarditis

Answer 29

ceftriaxone