Gradual loss of vision Flashcards

1
Q

causes of gradual loss of vision

A

cataract, macular degeneration, glaucoma, diabetic retinopathy, hypertension, optic atrophy, slow retinal detachment

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

what is the main cause of blindness

A

age related macular degeneration

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

what part of the vision is lost in age related macular degeneration

A

central vision (peripheral is maintained)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

dry age related macular degeneration

A

mainly drusen and degenerative changes at macula. slow progression

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

wet age related macular degeneration

A

new vessels grow from choroid into retina and leak. deteriorates quickly

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

features age related macular degeneration

A

progressive gradual loss of central vision- difficulty reading and recognising distant objects. peripheral vision maintained so can navigate. pupil reactions normal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

what can wet age related macular degeneration present like

A

vision deteriorates quickly. distorted images- straight lines wavy.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

when are drusen usually first deposited

A

after age 45 years, but asymptomatic then

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

what investigation can be done age related macular degeneration if suspecting choroidal neovascularisation

A

fundus fluorescin angiogram. optical coherence tomography (OCT)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

management age related macular degeneration

A

intravitreal VEGF inhibitors- bevacizumab and ranibizumab (wet); laser photocoagulation(wet); intravitrealsteroids; antioxidants and vitamins

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

pathogenesis open angle glaucoma

A

aqueous humour drains through trabecular meshwork in angle between cornea and iris. over time it undergoes morphological change. rise in IOP transmitted to optic disc where nerve fibre damage occurs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

risk factors open angle glaucoma

A

genetic, increasing age, DM, myopia, black race, thin cornea

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

features open angle glaucoma

A

no symptoms until so advanced that central vision is threatened, no headache, eye pain, loss acuity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

signs open angle glaucoma

A

increased IOP, optic disc cupping, peripheral visual field loss

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

optic disc exam open angle glaucoma

A

rim becomes pale and cup enlarges. cup:disc ratio

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

what cup:disc ratio suggests glaucoma

A

0.6. also asymmetry between the eyes of 0.2 is significant. (normal 0.4-0.7)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

how to examine optic disc

A

stereoscopic viewing through a dilated pupil. OCT optical coherence tomography

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

visual field defect open angle glaucoma

A

central scotoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

treatment open angle glaucoma

A

prostaglandin analogues- latanoprost, travoprost- incr aqueous outflow through uveoscleral route rather than trabecular meshwork; B blockers to reduce production humour- timolol, betaxolol; alpha adrenergic agonists- brimonidine; carbonic anhydrase inhibitors; miotics- pilocarpine; sympathomimetics

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

surgery option in open angle glaucoma

A

trabeculectomy

21
Q

which fields are lost first inopen angle glaucoma

A

nasal and superior fields, temporal are lost last

22
Q

what is optic disc cupping

A

loss of disc substance. if >0.9 cup:disc ratio then severe cupping

23
Q

what is a cataract

A

opacity in the lens

24
Q

what happens to the red reflex in cataract

A

still present in an immature cataract, but absent in dense cataract

25
Q

what morphological variants can occur with cataract

A

nuclear sclerosis- common in old age, subcapsular- shallow opacification can be from steroid use; cortical; dot opacities

26
Q

pre senile cataract causes

A

diabetes, corticosteroid therapy, atopy, galactosaemia, hypocalcaemia, dystrophia myotonica

27
Q

causes of congenital cataract

A

1/3- autosomal dominant. 1/3- birth trauma or maternal infection- rubella, toxoplasmosis.

28
Q

presentation cataract

A

blurred vision, unilateral often unnoticed but loss of stereopsis affects distance judgment. bilat causes loss of vision, dazzle, monocular diplopia

29
Q

how may cataract present in children

A

squint, loss of binocular function, white pupil, nystagmus

30
Q

treatment of cataract

A

prior to surgery- ocular biometry. surgery- lens extracted and another lens inserted- Perspex, acrylic, silicon. antibiotic and anti-inflammatory drops post op

31
Q

post op complications after cataract

A

posterior capsule thickening, astigmatism, eye irritation, rare- VH, retinal detachment, glaucoma

32
Q

prevention cataract

A

photoprotection- sunglasses. UV-B. decrease oxidative stress

33
Q

signs in optic atrophy

A

discs are pale. may be from incr IOP or retinal damage (choroiditis, retinitis pigmentosa); or ischaemia

34
Q

causative toxins optic atrophy

A

tobacco, methanol, lead, arsenic, quinine, carbon bisulfide

35
Q

causes optic atrophy

A

toxins, lebers optic atrophy, MS, syphilis, tumours

36
Q

what is visual loss usually due to in diabetic retinopathy

A

vitreous haemorrhage, maculopathy

37
Q

what happens in diabetic retinopathy

A

accelerates formation age related cataract, causes ocular ischaemia-new blood vessels to form on iris leads to glaucoma if prevents drainage of the aqueous fluid

38
Q

classification diabetic retinopathy

A

background, pre proliferative and proliferative

39
Q

what does vascular occlusion lead to diabetic retinopathy

A

ischaemia and new vessels forming in retina, otic disc, iris- proliferative retinopathy

40
Q

features of background retinopathy

A

microaneurysms, dot and blot haemorrhages, exudates

41
Q

features pre proliferative

A

cotton wool spots, venous beading, exudates

42
Q

features proliferative

A

new vessels at the disc, and elsewhere. cotton wool spots, flame shaped haemorrhages- ruptured microaneurysms

43
Q

what do cotton wool spots show

A

ischaemic nerve fibres

44
Q

what is maculopathy

A

leakage from vessels close to the macule cause oedema and threaten vision

45
Q

treatment diabetic retinopathy

A

good control diabetes, keep BP

46
Q

what can you treat diabetic macular oedema with

A

intravitreal triamcinolone and anti VEGF drugs

47
Q

what can be a complication in diabetic retinopathy

A

vitreous haemorrhage

48
Q

what factors can accelerate retinopathy

A

pregnancy, dylipidaemia, icr bp, renal disease, smoking, anaemia