GPhC Questions - TO KNOW Flashcards
Schedule + Requirements of Temazepam?
Schedule 3
Safe Custody Requirements
Within how may days do you have to supply someone with their own confidential information they have requested?
20 Days
What are the CPD requirements?
4 CPDs - 2 unplanned
Reflective Account - on 1 of 3 standards
Peer Discussion
What is the antibiotics of choice for a human/animal bite?
Co-Amoxiclav for 5 days
Alt in allergy: Metronidazole + Doxycycline
Alternatives in pen allergy for treatment of cellulitis?
Clarithromycin OR Doxycycline
What is the vaccine boosterix/infranix for?
Pertussis - Whooping Cough
What are the laxatives of choice in opioid-induced constipation?
stimulant + osmotic
= senna + lactulose
What are the step-wise treatments for management of chronic constipation?
Bulk-Forming
Osmotic
Stimulant
What are the step-wise treatments for management of acute constipation?
Bulk-Forming THEN
- Osmotic if hard stools
- Stimulant if loose stools
What are good prescribing points when prescribing insulin?
- write ‘units’ out in full
- don’t use syringes marked in mL, need them in units
What is the highest recommended dose for beclomethasone?
800mcg BD
e.g. clenil 200 = 2 PU BD
Who is responsible for ensuring the pharmacy meets the standards?
pharmacy owner + superintendent pharmacist
Patient is stable on Lithium, how often do they need to be monitored?
weekly until stable then every 3 months, then 6 monthly
BUT if any of these, need 3 monthly checks:
- Over 65s
- Drugs that interact with lithium
- Impaired renal/thyroid function
- Raised calcium levels
- Poor symptom control/adherence
- if last Lithium level was 0.8 or higher
What to do if peak/trough levels too high?
PEAK - reduce DOSE, as no matter how long you leave it will always get a peak that’s too high if you don’t change dose
TROUGH - increase INTERVAL - as the body needs more time to clear the drug
What is the interaction between ephedrine and phenelzine?
HYPERTENSIVE crisis = need to avoid for 14 days after stopping MAOI
What is the interaction between Warfarin + Tramadol?
increased risk of BLEEDS
- tramadol works on serotonin receptors so would have similar effect to that of SSRIs
Why is calcium in impaired renal function an issue?
when kidneys fail, calcium becomes unbalanced
What is molloscum?
viral infection that causes small raised red spots with a dimple on the middle - usually armpit, behind knees, groin
self-limiting and goes away on its own
What is the mechanism of action of dabigatran?
THROMBIN inhibitor
not factor 10a like the others
What is a bio similar?
same thing as what a generic is for a normal medicine, but for biologics instead
so biologics are too difficult to replicate exactly by other manufacturers, so their biologics they make after the patent is a ‘biosimilar’
What is a side effect of Finasteride?
breast abnormalities in males
Why should you be careful when taking desmopressin when swimming?
children - may ingest a lot of water, desmopressin would stop uresis of this and lead to hypernatraemia
Incidence of side effects no.s + how common?
> 1 in 10 = VERY common
1 in 10 - 1 in 100 = COMMON
1 in 100 - 1 in 1000 = uncommon
1 in 1000 - 1 in 10,0000 = rare
OTC naproxen conditions?
- PRIMARY dysmenorrhoea (not due to PCOS or anything)
- age 15 - 50 years
- max duration = 3 days
- max single dose = 250mg
- max daily dose = 750 mg (1 tab TDS)
- max pack size is therefore 9 tabs (3 tabs a day for 3 days)
Reversal agent for Dabigatran?
- its a MAB = Idarcizumab
all the others are adexenet alfa
Is carbamazepine teratogenic?
YES - major malformations
Drug for hyptertension in pregnancy + dose?
Labetalol
- 100mg BD initially, usual dose 200mg BD
Warning labels for β blockers?
don’t stop unless told - can cause rebound tachycardia
Lithium + NSAIDs interaction?
NSAID cause increase in lithium concentrations
both processed by kidneys
Allopurinol + Azathioprine/Mercaptopurine interaction?
allopurinol enhances haematological toxicity
so Azathioprine dose has to be reduced by a quarter
Can angioedema be a side effect of ACE?
YES
What is the chloramphenicol eye drop dose for conjunctivitis?
1 DR every 4 hours for first 48 hours
THEN
1 DR every 6 hours up until 5 days max
REFER if not improving within the 48 hours
What is the minimum age of babies to treat oral thrush with miconazole gel?
4 months
TRUE or FALSE. Levothyroxine has a side effect of hair loss.
TRUE.
Criteria for Amorolfine
NO more than 2 nails infected to sell OTC
Prescriber’s request for emergency supply, when to get the prescription?
within 72 hours
Patient has already tried Olanzapine + Haloperidol, which antipsychotic next?
1 is typical, 1 is atypical so can now have Clozapine (treatment-resistant schizophrenia)
eGFR cut off for Nitrofurantoin?
< 30 if treating as short-course
True or False. Can give Naloxone in an emergency in the same way you can give adrenaline?
TRUE.
Purpose of the HPV vaccine?
Cervical Cancer
Side effect of Spironolactone?
Gynaecomastia
What can be given for an acute dystonic reaction with metoclopramide?
Procyclidine
What is the CPR: Breaths ratio?
30:2
What juice does Ciclosporin interact with?
Grapefruit
True or False. Metformin causes taste disturbances.
TRUE
When is a BuTrans patch changed?
Weekly - every 7 days
What electrolyte imbalance does Salbutamol cause?
hypokalaemia
4-year-old Child on Salbutamol and ICS. Asthma uncontrolled. What medication do you recommend?
Montelukast
