GP Flashcards

1
Q

Acute bronchitis: definition, cause, symptoms

A

Definition: inflammation of the bronchial airways without pneumonia

Causes: Rhinovirus, influenza parainfluenza and coronavirus

Symptoms: Breathlessness, wheeze, pleuritic pain, fever, sore throat, rhinorrhoea. Diagnosed clinically

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2
Q

Acute Bronchitis management

A
  • outpatient, stop smoking, over the counter remedies
  • Safety netted for worsening or persistent symptoms
  • Doxycyline if CRP >100 or the person is >65 and/or has comorbidities
  • If CRP >20 can offer delayed prescription
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3
Q

Acute bronchitis: complications and prognosis

A

Mild and self limiting, though cough may persist up to 6 months. Can be complicated by development of pneumonia

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4
Q

Anal fissure: risk factors

A
  • constipation
  • Pregnancy
  • inflammatory bowel disease
  • sexually transmitted infections e.g. HIV, syphilis, herpes
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5
Q

Anal fissures: features

A
  • painful, bright red, rectal bleeding
  • Anal spasms, skin tag can be visible
  • Majority occur on posterior midline, if not consider Crohns
  • Inv: clinical, can do digital rectal exam if tolerates
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6
Q

Management of acute anal fissure <1 weeks

A
  • soften stool
    • dietary advice: high-fibre diet with high fluid intake
    • bulk-forming laxatives (Ispaghula husk) are first-line - if not tolerated then lactulose should be tried
  • lubricants such as petroleum jelly may be tried before defecation
  • topical anaesthetics: lidocaine cream
  • analgesia
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7
Q

Management of a chronic anal fissure

A
  • Laxatives and lubricants
  • Topical GTN (nifedipine) is first line, second line is topicl calcium channel blockers or oral nifedipine
  • If topical GTN isnt effective after 8 weeks then secondary care referral should be considered for surgery (sphincterotomy) or botulinum toxin
  • If fissure <6 weeks they are acute if >6 weeks they are chronic
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8
Q

Bells palsy

A

Bell’s palsy is an idiopathic syndrome that causes damage to the facial nerve leading to a lower motor neuron facial palsy. Tends to affect 20-40 and pregnant women

No known cause might be due to viral reactivation of HSV-1 or EBV

Diagnosis is primarily clinical

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9
Q

Bell’s palsy signs and symptoms

A
  • Acute but not sudden onset of unilateral lower motor neuron facial weakness, tends to affect the forehead
  • Postauricular otalgia which might precede the paralysis
  • Hyperacusis, dry eye
  • Nervus intermedius symptoms, such as altered taste and dry eyes/mouth.
  • ‘Numbness’ or ‘heaviness’
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10
Q

Management of Bell’s palsy

A
  • 50mg of oral prednisolone followed by a taper
  • Supportive treatment: artificial tears and lubricants and eye patch
  • Long term: pain management, physical therapy, counselling
  • Most people fully recover but a small proportion have incomplete recovery
  • If paralysis not resolved in >3 weeks refer to ENT
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11
Q

Blepharitis

A

Inflammation of the eyelid, leading cause of dry eye disease. Symptoms: bilateral ocular irritation, foreign body sensation, burning, redness, crusting. Causes: atopic dermatitis, seborrheic dermatitis, acne rosacea, Demodex mites.

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12
Q

Blepharitis treatment

A

lid hygiene (warm compress, eyelid massage, cleaning), topical antibiotics (chloramphenicol), low-dose oral tetracyclines, omega-3 supplements.

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13
Q

Hordolum (stye) definition and treatment

A

Staphylococcal infection of an eyelash follicle (external) or meibomian gland (internal). Presents as tender, red eyelash follicle swellings.

  • Treatment: warm compress, eyelash removal, incision with a sterile needle, topical/oral antibiotics if recurrent or severe.
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14
Q

Chalazion definition and treatment

A

Non-infectious granulomatous inflammation of a meibomian gland. Presents as painless red eyelid cysts. Often associated with blepharitis and acne rosacea.

  • Treatment: warm compress, eyelid massage. Persistent cases require ophthalmology referral for incision and curettage.
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15
Q

Entropion definition and treatment

A

Inward turning of the eyelid, leading to corneal irritation and potential ulceration. Causes: age-related changes, eyelid irritation, scarring, trachoma.

  • Treatment: examine for corneal abrasions/ulcers, prescribe lubricants, advise eyelid taping, refer for surgical correction.
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16
Q

Ectropion definition and treatment

A

Outward turning of the eyelid, often due to age-related changes or facial nerve palsy (Bell’s palsy). Presents with a sore, red, watery eye due to disrupted tear drainage.

  • Treatment: lubricating eye drops, taping eyes shut at night, corrective surgery for severe cases. Urgent referral for exposure keratopathy.
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17
Q

Trichiasis definition and treatment

A

Inward-growing eyelashes due to damaged follicles, causing corneal irritation and potential ulceration. Often due to chronic blepharitis.

  • Treatment: epilation of eyelashes, electrolysis, or laser ablation for more permanent solutions. Examine for corneal damage.
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18
Q

BPH: definition, symptoms and Investigations

A

Definition: non-malignant enlargement of the prostate gland. Occurs with age, can compression of the urethra and LUT’s symptoms.

Symptoms: Hesitancy, weak stream, frequency, urgency, nocturia, sensation of incomplete emptying

Investigations: assess IPSS score, digital rectal exam, do PSA if suspect prostate cancer.

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19
Q

Management of BPH

A
  • Alpha blockers like Tamsulosin and 5-alpha reductase inhibitors i.e. Finasteride
  • Alpha blockers offered if IPSS >8 provides symptomatic relief but doesn’t affect prostate size. Dont give if falls risk. First line
  • High risk of progression and enlarged prostate: 5-alpha reductase inhibitors (reduce prostate size)
  • Surgery: TURP or laser prostatectomy
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20
Q

Breast abscess: definition, cause, symptoms, investigations

A

The accumulation of pus within an area of breast tissue, often a complication of infectious mastitis

Cause: S.aureus

Symptoms: Fever, malaise, breast pain, erythema, fluctuant mass

Investigations: US, Needle aspiration (diagnostic and therapeutic)

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21
Q

Breast abscess management

A
  • Incision and drainage if >5cm or needle aspiration if <5cm
  • Oral or IV abx i.e. Flucloxacillin
  • Continue to express breast milk
22
Q

Olecranon bursitis

A
  • Inflammation and swelling of the bursa over the elbow over the ulna
  • Cause: repetitive movement, leaning on elbow
  • Presentation: swollen, warm, tender, fluctuant
  • Management: rest, ice, analgesia, protect elbow from pressure. Aspiration of fluid can relieve pressure. Steroids if severe

Only aspirate if suspect infection

23
Q

Trochanteric bursitis

A
  • Inflammation of the bursa over the greater trochanter of the femur
  • Causes; friction from repetitive movement, trauma
  • Presentation: lateral hip pain, swelling and positive trendelenberg test
  • Inv: MRI or US
  • Management: analgesia and physio. Steroid if refractory. Severe cases surgical removal of the bursa (bursectomy)

Only aspirate if suspect infection

24
Q

Conjunctivitis: definition and causes

A

Definition: ‘pink eye’ inflammation (due to allergies) or infection of the conjunctiva

Causes of conjunctivitis
- Allergic: triggers include pollen, dust mites and pet dander. Most common type
- Viral: Tend to be adenovirus or Herpes simplex. Highly contagious. Associated with URTI
- Bacterial: S.aureus, S.epidermis, S.pneumonia. Can also be caused by sexually transmitted infections

25
Q

Conjunctivitis signs and symptoms

A
  • Eye redness
  • Itching
  • Irritation
  • Excessive tearing
  • Discharge from the eyes: viral is watery, bacterial is purulent (can cause eyelids to stick together)
  • Photophobia, which suggests corneal involvement (keratoconjunctivitis)

Investigations: normally clinical but can take a swab if dont respond to treatment

26
Q

Neonatal conjunctivitis

A

neonates under one month with conjunctivitis need urgent opthalmology assessment. May be caused by gonococcal infection which can cause permanent vision loss.

27
Q

Management of conjunctivitis

A
  • Allergic: avoid allergens, artificial tears, topical antihistamine, or mast cell stabilisers such as topical sodium cromoglycate
  • Viral conjunctivitis: supportive
  • Bacterial: tends to be self limiting but can prescribe topical antibiotics i.e. chloramphenicol and fusidic acid (for pregnant women).
  • Conjunctivitis associated with contact lenses: give an aminoglycoside (e.g. gentamycin) or a quinolone (e.g. levofloxacin or moxifloxacin). Topical fluoresceins should be used to identify any corneal staining. Stop wearing contacts until symptoms resolve and antibiotics complete
  • Dont share towels if infective
28
Q

Constipation diagnosis

A
  • Fewer than three bowel movements per week
  • Hard stool in more than 25% of bowel movements
  • Tenesmus (sense of incomplete evacuation) in more than 25% of bowel movements
  • Excessive straining in more than 25% of bowel movements
  • A need for manual evacuation of bowel movements
  • Can either be primary or secondary

Risk factors: age, inactivity, low calorie diet, high fibre diet, certain medications, female

29
Q

Causes of constipation

A
  • Dietary factors: inadequate fibre or fluid intake
  • Behavioural factors: inactivity (common cause of constipation in inpatients) or avoidance of defecation
  • Electrolyte disturbances: hypercalcaemia
  • Certain drugs, particularly opiates, calcium channel blockers and some antipsychotics
  • Endocrine disorders: hypothyroidism
  • Colon diseases: strictures or malignancies.
  • Anal diseases: anal fissures or proctitis
30
Q

Contact dermatitis: risk factors and inv

A

Risk factors: FH, occupational exposure (metal worker, healthcare, beutician), cosmetics

Normally clinical diagnosis but can confirm with patch testing and skin biopsy

31
Q

Contact dermatitis

A

inflammation of the skin from due to direct contact with a substance that irritates the skin or provokes an allergic response

32
Q

ALARM features which may indicate GI malignancy include

A

anaemia, weight loss, anorexia, recent onset, melaena/haematemesis/PR bleeding, swallowing difficulties

33
Q

Types of contact dermatitis

A
  • Irritant contact dermatitis: eczema due to contact with an irritant, localised to area of contact. Common with detergents and bleach. Associated with occupations that handle irritating material
  • Allergic contact dermatitis: itchy, eczematous rash (vesicles, erythema) 24-48hrs after exposure. May extend beyond contact zone. Typical allergens are nickel, acrylate, fragrence, rubber, plastic. Type 4 hypersensitivity reaction, acute weepy eczema. Treat with potent steroid
34
Q

2WW constipation

A
  • Constipation (or diarrhoea) with weight loss, 60 and over. Consider an urgent, direct access CT scan, or an urgent ultrasound scan if CT is not available, to rule outpancreatic cancer
  • FIT test if concerned about colorectal cancer
35
Q

Types of laxatives

A
  • Bulking agents; for example Ispaghula Husk
  • Stimulant: i.e. Senna. Used for short term relief of constipation
  • Stool softeners i.e. sodium Docusate, Macrogol. Used in fissures
  • Osmotic laxative i.e. lactulose. Used in HE
  • Phosphate enema. Used for rapid bowel evacuation often before a medical or surgical procedure
35
Q

Constipation management

A
  • Lifestyle: dietary improvements and increased exercise
  • Laxatives: if they fail refer to specialist centre
  • Use bulk forming laxatives first line then osmotic
36
Q

Contact dermatitis management

A
  • Avoidance: 8-12 weeks before improvements may be seen
  • Emollients, oral antihistamine
  • Topical steroids: to control symptoms
  • Workplace modifications and protective measures may be needed: use of gloves
  • Refer to dermatology if severe, chronic, difficult to treat or thought to be associated with occupation
37
Q

Cutaneous fungal infection

A

also known as tinea corporis or ringworm are dermatophyte infections of the superficial infection of the skin. Tinea cruris affects the groin.

38
Q

Aetiology of cutaneous skin infection

A
  • Tinea corporis (body) is caused by Trichophyton rubrum and Tinea cruris (groin) is caused by Epidermophyton floccosum
  • Tinea capitis affects the scalp, tinea pedis affects the feet, onchomycosis is fungal nail infection
  • Spread by direct and indirect (towels) contact
  • Risk factors: exposure to infection, immunosuppression, T2D, obesity
39
Q

Clinical features of fungal infection and inv

A
  • Patchy skin lesions which may be red or pink edged surrounding a central clearing and grow outwards
  • Skaly, itchy
  • Often in skinfolds, including the groin

Clinical diagnosis but can do skin biopsy and culture. Test HBA1c or HIV if recurrent

40
Q

Management of cutaneous fungal infection

A
  • Conservative: dont share towels, wear loose fitting clothes
  • Mild disease: topical terbinafine or imadazole/fluconazole (antifungals)
  • Severe or widespread: oral terbinafine or oral fluconazole
  • Terbinafine: dont use if hepatic impairment, check LFT’s prior to treatment and after 4-6 weeks
  • Fungal nail infection: amorolfine nail lacquer for 6-12 months, resistant cases need oral terbinafine
  • A mild topical steroid can help with itching and inflammation i.e. Miconazole 2% and hydrocortisone 1% cream.
41
Q

Tinea capitis (scalp ringworm)

A
  • Can cause scarring alopecia or a kerion (spongey mass) if untreated
  • Causes: Trichophyton tonsuran, Microsporin canis
  • Diagnosis: scalp scrapings
  • Management: oral antifungals like terbinafine. Topical ketoconazole shampoo is given for the first two weeks to reduce transmission
42
Q

Tinea incognito

A

when a fungal skin infection has been treated with steroids. Can dampen immune response causing it to spread further but the rash becomes more mild.

43
Q

Genital warts

A
  • Caused by HPV 6 and 11, STI
  • Small skin coloured growths in the genital area
  • Painless
  • Either keratinised (hard) or non-keratinised (soft)
  • Clinical diagnosis can do biopsy
  • Management: Podophyllotoxin or Imiquimod. Can use Cryotherapy (freezes wart)
44
Q

Cutaneous warts: what are they

A
  • I.e. varrucas
  • Benign epithelial proliferations caused by HPV
  • Hyperkeratotic papules with rough surfaces
  • Caused by HPV types 1, 2 and 4
  • Normally found on the hands, feet and face
45
Q

Cutaneous warts: inv and management

A
  • Either clinical or dermoscope
  • Management: topical salicylic acid (first line), Podophylotoxin (for anogenital warts)
  • Surgery: Cryotherapy or surgical excision or laser therapy
46
Q

Classification of cutaneous warts

A
  • Common warts (verruca vulgaris): typically found on the hands. Firm hyperkeratotic papule with roughened surface
  • Flat warts (Verruca plana): smooth, flat topped papules. Appear in large numbers on the face, dorsum of hands and shins
  • Plantar warts (Verruca Plantaris): located on the sole of feet and other weight bearing areas. Flat appearance with central black specks
  • Anogenital warts: genital reign, variable appearance
47
Q

Dementia

A
  • A progressive and chronic syndrome which involves impairment of multiple higher cortical functions like memory, thinking, orientation, comprehension and language
  • Can be primary or secondary to another condition
  • Early onset dementia is <65
  • A mini-mental state examination (MMSE) score of 24 or less out of 30 suggests dementia with scores of 20-24 mild, 13-20 moderate, and <12 severe.
48
Q

Primary dementia and findings in the brain

A
  • Tauopathies with Beta-Amyloid: Alzheimer’s Disease
  • Tauopathies without Beta-Amyloid: Fronto-Temporal Dementia, Corticobasal Degeneration, Progressive Supranuclear Palsy
  • Alpha-synucleinopathy: Lewy Body Dementia, Parkinson’s Disease, Multiple System’s Atrophy
  • Polyglutamine disorders: Huntington’s Disease
  • Vascular dementia
49
Q

Secondary causes of dementia

A
  • Infectious: Neurosyphilis, Encephalitis/Meningitis, AID’s dementia complex
  • Trauma
  • Toxins: alcohol
  • Autoimmune: Sarcoidosis, late stage MS
  • Metabolic: B1, B12, B9 deficiency, hepatic encephalopathy
  • Endocrine: hypothyroidism and hypoparathyroidism