GP Flashcards
Diagnosis of Diabetes
Clinical symtoms (polyuria, polydipsia, unexplained weight loss) + random glucose or 2 hr 75 g glucose test >11 mmol/l + fasting glucose >7 mmol/l
Rapid Acting Insulin
Lispro, aspart, or glulisine
Long Acting Insulin
Insulin detamir (Levemir) lnsulin glargine (Lantus)
5 causes of Secondary Hypertension
CHAPS - Cushings, Hyperaldosteronism, Aortic Coarctation, Pheochromocytoma, Stenosis of the renal artery
Female Athlete triad
ammenorhea, eating disorder, osteoporosis
Treatment of chalmidya and gonorrhea
Gonorreha - ceftraixone 125 mg IM single dose and chlamidya - doxycline 100 mg BID 7 DAYS or azithromycin 1 g orally
Warfarin therapy indications
first episode DVT with transient risk factors: 3 months first episode DVT with ongoing risk factors - consider indefinite therapy first episdoe with no identifiable risk factors - 6-12 months or indefinite recurrent - indefinite
Treatment of acute sinusitis
symptoms improving within 5 days - symptomatic moderate symptoms that persist for more than 5 days - corticosteroids severe and resistant to corticosteroids - clarithromycin
Impotence
Inability to achieve or maintain an erection
Min number of sperm needed for pregnancy
1 million
Treatment of cluster headaches
abortive - oxygen, triptans, octreotide, dihyrdoergotamine prophylaxis - verapmail, ergotamine, prednisone, indomethacin
Hypercholestermia and HTN
beware that statins and verapamil together can lead to rhabdomyolysis and verapamil inhibits cytochrome p450 that normally breaks down statins
Treatment of V tachycardia
Amiodarone
Most common fractured bone in lower leg in children
Tibia
Prevntion of contrast induced nephropathy
Hydration with sodium bicarbonate
Indications for tonsillectomy
Recurrent, confirmed bacterial tonsillitis (>4 times/year), irrespective of the type of bacteria Compliations of acute tonsillitis such as peritonsilar abscess or septicaemia originating from the tonsils Peritonsillar abscess in a patient <40 years of age Suspected malignancy including marked asymmetry or ulceration Airway obstruction caused by sleep apnea, tonsils or disorder of dental occlusion Chronic tonsillitis is a relative indication – if causing bad breath, sore throat, gaggin and symptoms do not decrease with follow up
Treatment of athletes foot
Before putting on anti-fungals need to diagnose by taking a culture of scrappings - terbinafine 250 mg once/day for 12 weeks or itroconazole 200 mg bid 1 week/month for 3 months
Best initial therapy for acute cardiogenic pulmonayr edema
LMNO Loop Diuretics Morphine (venous dilation decreases preload) Nitrates Oxygen
Rhinitis medicamentosa
If you use decongestants for more than 3 days you get a rebound congestion on drug withdrawal. When used for several months, these agents can cause a rhinitis that is difficult to treat
Xerosis
pathologic drying of the that is especially common in the elderly and exacerrabated by winter and low humidity
Treatment of central vs nephorgenic DI
Central - vasopressin or desmopressin Nephrogenic - diuretics
Complications of nasogastric feeding
Diarrhea (most comon) - add anti-diarrheal agents to feed, aspiration, ucleration of nasal and esophageal tissues leading to strictures
Breast cancer incidence
1 in 9 will be diagnosed and 1 in 27 will die from breast cancer
Match elevated ACE elevated methylmanionic acid reduced haptoglobin elevated protoporphyrin
elevated ACE - sarcoidosis elevated methylmanionic acid - vitamin b12 deficiency reduced haptoglobin - hemolytic anemia elevated protoporphyrin - lead poisoning or iron deficiency
Preferred antibiotics for anerobic infection in the mouth
Clindaymycin or amoxicillin
Treatment of acne
Mild - topical benzoyl peroxide and/or topical antibiotics (erythromycin, clindamycin Moderate - Tetracycline, Doxycycline, erythromycin Severe - Oral isoretinoin (Accutane)
Causes of acanthosis nigricans
DM2 Obesity Familial Drung induced Malignant (gastric cancer) PCOS
Preferred site for emergent airway entry is
Through cricothyroid membrane above the cricoid cartilage. Note that during controlled circumstances, the preferred site would be the between the tracheal rings or thyroid isthmus
Patients taking isoniazid should also take what
Vitamin B6 (Pyridoxine) otherwise can result in coma, seizures, pins and needles sensation
Medical Management of Aortic Dissection
Beta blocker to decrease BP to 110 mmHg followed by nitroprusside
Thrombolytics contraindications
Severe hypertension Stroke within the preceeding 2 months Active bleeding Surgery within the preceeding 2 months Neoplasms or vascular abnormalities
Thrombolytics contraindications
Severe hypertension Stroke within the preceeding 2 months Active bleeding Surgery within the preceeding 2 months Neoplasms or vascular abnormalities
Secondary causes of osteoporosis
Decreased BMI Corticosteroids Vitamin D deficiency Excessive alcohol Hypogonadism
Differential Diagnosis for Hematuria
Generalized Medication - anti- coagulants Hemoglobinopathies - Anemia Leukemia Localized Neoplasm Infection - Tuberculosis, UTI Trauma Stones Glomerulonephritis
Casue of rheumatic Fever
Group A beta hemolytic streptococcus
Radical Prostatecomy
Prostate, seminal vesicles and ampula of vas deferens are removed
Investigations and treatment for BPH
Ix: Urine fr microscopy and culture, U&E to assess renal function, PSA. Urine flow test to see flor and urinary volume against time. U/S to assess urinary bladder volume and upper tract dilatation. Transrectal ultrasound and biopsy if BPH suspected. Voiding diary to see how bothersome symptoms are to patients
Tx:
Conservative - watchful waiting if symptoms are mild
Medical - alpha blockers which relax the prostatic smooth muscle tone increasing urinary flow and helping with obstructive symptoms. Side effect: Postural hypotension
5 alpha reductase inhibitors which block the conversion of testosterone to the more potent dihydrotestosterone
Surgical - Transurethral resection of the prostate (TURP) - patient palced in lithomy position and a resectoscope placed through urethra and diathermy is used to cut away the prostate. Diathermy is also used to minimize bleeding. Three way cathether is used to irrigate the bladder until the fluid is no longer blood stained
[Complications of TURP
General vs Specific
Early vs late
Early : Septic shock, bleeding and transurethral syndrome (absorption of hypotonic irrigation leading to electrolyte abnormalities 0 hyponatremia, fluid overload and hemolysis, brain edema. Treat transurethral syndrome with fluid restriction, diuretics and close observation. Note that saline solution cannot be used as it limits the use of diathermy
Late: Secondary hemmorhage, urethral strictures, impotence (65-80% experience retrograde ejaculation), recurrent prostatic growth and recurrent symptoms