Gout

Question 1

What joints are more likely involved with gout?

Answer 1

foot and ankle

Question 2

What joints are more likely involved with pseudogout?

Answer 2

Knee and other joints

Question 3

What crystals are in gout?

Answer 3

monosodium urate (needle-shaped)

Question 4

What crystals are in pseudogout

Answer 4

calcium pyrophosphate (rhomboid-shaped)

Question 5

Which condition has negatively birefringent crystals?

Answer 5

gout

Question 6

Which condition has positively birefringent crystals?

Answer 6

pseudogout

Question 7

What are the risk factors for gout?

Answer 7

Male, HTN, Diabetes, obesity, HLD

Question 8

What should patients with gout avoid?

Answer 8

ETOH, red meat, seafood, aspirin, thiazides

Question 9

What is the first-line treatment for gout?

Answer 9

NSAID’s and ice

Question 10

What therapies are used when NSAIDs can’t be used?

Answer 10

Colchicine, steroids, intraarticular injections

Question 11

What drugs are used for gout prophylaxis and what MOA?

Answer 11

Allopurinol prevents the formation of uric acid

Probenecid encourages renal excretion