Gordy Gastritisy Infection Flashcards

1
Q

Define gord.

A

oesophagitis secondary to refluxed gastric content into the oesophagus

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2
Q

Causes of GORD?

A
  • insufficient oesophageal sphincter tone
  • obesity
  • pregnancy
  • achalasia
  • big meals
  • smoking, alcohol, fatty meals, coffee
  • hiatus hernia
  • drugs - TCAs, NSAIDs, bisphosphonates
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3
Q

Sx of GORD?

A
  • Heart burn - retrosternal pain
    • aggravated by bending forward/lying down
    • relieved by antacids
  • regurgitation of food/acid
  • strange taste in mouth
  • odynophagia
  • cough/wheeze
  • chest pain - difficult to differentiate from IHD
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4
Q

How do diagnose GORD?

A
  • clinical
  • trial by PPI
  • OGD in certain pts
  • gold standard - 24hr oesophageal pH monitoring
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5
Q

indications for OGDing patient with GORD?

A
  • > 55
  • 4/52 Sx despite tx
  • dysphagia
  • weight loss
  • haematemesis
  • anaemia
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6
Q

Treatment of GORD?

A
  • lifestyle - lose weight, smaller meals, cut down triggers
  • gaviscon first line
  • PPIs next - omeprazole
  • H2 antagonist next - ranitidine
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7
Q

Surgical intervention for GORD?

A

-Nissen fundoplication

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8
Q

Complications of GORD?

A
  • oesophagitis
  • barrets oesophaus - oesophageal Ca
  • ulcers
  • anaemia
  • strictures
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9
Q

Most common causes of gastritis?

A
  • H. pylori
  • NSAIDs
  • alcohol
  • autoimmune - pernicious anaemia
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10
Q

Sx of gastritis?

A
  • GORD
  • epigastric pain - intermittent, worse on eating
  • loss of appetite - therefore weight
  • bloating
  • retching, nausea, vomiting
  • early satiety
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11
Q

Ix for gastritis?

A
  • mild = clinical diagnosis
  • gastroscopy +/- biopsy
  • H. pylori testing
  • Barium swallow
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12
Q

How do you treat gastritis?

A
  • treat like GORD
  • lifestyle advice + medication
  • Tx cause
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13
Q

Acute onset diarrhoea can frequently caused by infection. What are some examples of causative agents and where are they picked up?

A
  • viral - rotavirus, norovirus - contact with others affected
  • foodborne - bacterial - E.Coli, salmonella
  • antibiotic associated - wipe out of normal gut flora
  • travel related - giardiasis
  • systemic infection - malaria, sepsis
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14
Q

Definition of travellers diarrhoea?

A
  • 3 or more watery stools in 24hrs

- most common caused by E.coli

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15
Q

define food posioning?

A
  • acute onset N, V and D after ingestion of a toxin

- commonly S.aureus, C.perfrigens, B.cereus

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16
Q

Tell me about C.Diff?

A
  • gram +ve rod bacteria
  • found in hospital
  • normal gut flora supressed
17
Q

How do diagnose C.Diff?

A

-C.diff toxin in stool sample

18
Q

How do treat C.diff?

A
  • oral metronidazole 7-10 day
  • if fail - oral vancomycin
  • if severe - IV metronidazole + oral vancomycin
19
Q

What are the 5 Cs of C.diff?

A
  • cefotaxime
  • ciprofloxacin
  • carbapenem
  • clindamycin
  • co-amoxiclav