GORD/IBD

Question 1

GORD

Answer 1

M:F 2-3:1
5% daily Sx
smoking, alcohol, fat, coffee
hiatus hernia
pregnancy
drugs

Question 2

Sx of GORD

Answer 2

heartburn
acid/water brash
odynophagia
nocturnal asthma

Question 3

Complications of GORD

Answer 3

oesophagitis
peptic ulcers
benign strictures
Barret’s

Question 4

Barret’s oesphagus

Answer 4

sqaumous lined oesophagus–>columnar cells as seen in the stomach due to intestinal metaplasia

Question 5

triple therapy for H. pylori eradication

Answer 5

PPI + 2 antibiotics
NICE recommends a one-week triple therapy regimen as first-line eradication therapy. The optimum regimen, according to CKS, consists of a full dose proton pump inhibitor, with amoxicillin 1g and either clarithromycin 500mg, or (in the case of penicillin hypersensitivity) metronidazole 400mg and clarithromycin 250mg, all given twice daily

Question 6

adenocarcinoma stomach

Answer 6

3rd most common form of cancer death
most common proximally
causes: FH, diet, alcohol, smoking, H. pylori

Question 7

extraintestinal mainfestations of IBD

Answer 7

apthous ulcers (mouth), 
pyoderma gangrenosum, 
iritis, 
erythema nodosum,
sclerosing cholangitis, 
ank spond, 
clubbing

Question 8

skip lesions are found in?`

Answer 8

Crohns

Question 9

transmural involvement is found in?

Answer 9

Crohns