Good Pasture Syndrome Flashcards
1
Q
What is the pathophysiology behind good pasture syndrome?
A
Auto-antibodies against collagen type 4 in the renal and pulmonary capillary basements membrane. Possibly triggered by viral infections, lymphoma
2
Q
What are the clinical findings?
A
Haemoptysis
Cough
Dyspnoea
Nephritic syndrome
3
Q
What type of nephritis is good pasture syndrome?
A
Proliferative glomerulonephritis
4
Q
What are the lab findings for good pasture syndrome?
A
Anti-GBM antibodies