Gold Compounds

Question 1

Gold Compounds Drug Names

Answer 1

Auranofin

Question 2

Gold Compounds Therapeutic Actions

Answer 2

• Absorbed by macrophages, which results in inhibition of phagocytosis
• Tissue destruction is decreased

Question 3

Gold Compounds Indications

Answer 3

• Anti-arthritis

Question 4

Gold Compounds Contraindications and Cautions

Answer 4

Contraindications:
•	Known allergy
•	Diabetes
•	CHF
•	Renal or hepatic impairment
•	Blood dyscrasias
•	Pregnancy and lactation

Question 5

Gold Compounds DDI

Answer 5

DDI: 
•	Penicillamine
•	Antimalarials
•	Cytotoxic drugs
•	Immunosuppressive agents

Question 6

Gold Compounds Adverse Effects

Answer 6

• Stomatitis
• Glossitis
• Gingivitis
• bone marrow depression
• Dermatitis
• Interstitial pneumonitis
• Anaphylactic shock

Question 7

Gold Compounds:

Assessment

Answer 7

Assess:
Hx: allergy, any signs of infection,
Physical: vital signs, skin, temp, CNS status, cancer screening, monitor ROM, movement, and pain levels, respirations and adventitious sounds (baseline)
Labs: monitor

Question 8

Gold Compounds:

Diagnosis

Answer 8

Dx:

• Acute pain: to CNS disease process
• Risk for infection related to drug therapy
• Anxiety related to disease process and drug effects
• Deficient knowledge: drug therapy

Question 9

Gold Compounds:

Implementation

Answer 9

Implementation:
• Teach patient proper preparation, administration of subcutaneous injections
• Monitor for immune suppression reaction and CNS toxicity
• Arrange for continuation of nondrug therapies to deal with arthritis
• Ensure patient has routine cancer screening and regular follow-up
• Provide thorough patient teaching

Question 10

Gold Compounds:

Evaluation

Answer 10

Eval:
Response to the drug 
Adverse effects 
Effectiveness of comfort measures Compliance with the regimen
Effectiveness of the teaching plan