GOD NOTES Flashcards
What is this ?
And what is the treatment for it ?
Seborrhoeic keratosis
Benign, no treatment required.
If patient would like removal, then use cryotherapy and curettage.
What is this (immunosuppressed patient) ?
And what is the treatment ?
Dermatofibroma.
Benign, no treatment required.
Which is more superficial - bullous pemphigoid or pemphigus vulgaris ?
Describe their locations.
Pemphigus vulgaris is more superficial - think of acne
Pemphigus vulgaris = intra-epidermal
Bullous pemphigoid = sub-epidermal
Type II hypersensitivity - IgG4 antibodies against desmosomal proteins lead to loss of keratinocyte adhesion.
What condition is this ?
Pemphigus vulgaris
Which HLA haplotype is associated with dermatitis herpetiformis ?
HLA-DQ2
What antibody is found in dermatitis herpetiformis ?
Anti-TTG
Treatment for dermatitis herpetiformis ?
Gluten free diet +/- Dapsone
1st, 2nd and 3rd line management of rosacea
- 1st line: topical metronidazole
- 2nd line: topical therapies + oral antibiotics (doxycycline)
- 3rd line: isotretinoin
Humeral shaft fractures injure what nerve ?
Radial nerve
What is Koebner’s phenomenon ?
Psoriasis develops in an area of trauma
1st, 2nd and 3rd line management for psoriasis in primary care
1st: Topical corticosteroid + topical vitamin D analogue, applied once each daily at different times
2nd: stop steroid and apply Vitamin D analogue twice daily
3rd: stop Vitamin D analogue and apply corticosteroid twice daily
Secondary care management for psoriasis
Phototherapy
Immunouppression (methotrexate) or immune modulation (biologics)
What are lichenoid conditions ?
Damage to the basal epidermis
What type of hypersensitivity reactions are pemphigus and pemphigoid ?
Type II
What type of skin reactions are type I hypersensitivity ?
Anaphylaxis, urticaria