Derm Formative Week 1 Flashcards

1
Q

Component of MRSA which causes necrotising fasciitis

A

PVL

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2
Q

Blisters on dorsal aspect of hands, fragile skin, hypertrichosis of the malar region

A

Porphyria cutanea tarda

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3
Q

Anagen
Catagen
Telogen

Which phases ?

A

Anagen = Growing phase
Catagen = Involuting phase
Telogen = Resting phase

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4
Q

Where are Langerhans cells produced ?

A

Bone marrow

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5
Q
A

Bulla
Papule
Plaque
Pustule
Nodule
Wheal
Vesicle
Macule

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6
Q

During foetal development, which skin layer is most metabolically active ?

A

Basal layer

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7
Q

Which cells carry out Vitamin D metabolism ?

A

Keratinocytes

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8
Q

Acute intermittent porphyria = deficiency of which enzyme ?

A

Porphobilinogen deaminase

(causing an accumulation of porphobilinogen)

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9
Q

Which cells produce collagen ?

A

Fibroblasts

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10
Q
A

A= Keratin layer
B=
C = Melanocytes
D = sebaceous gland
E =
F = epidermis and dermis,
G = fibroblasts
H = sebaceous gland
I = Arrector pili muscle
J = Papilla and matrix of hair follicle

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11
Q

Type I hypersensitivity =

A

Immediate hypersensitivity

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12
Q

Type II hypersensitivity

A

Direct cell killing

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13
Q
A

A is the keratin layer.

B is the granular layer.

C is the prickle cell layer.

D is the basal layer.

E is the dermo-epidermal junction,

F is the dermis

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14
Q

Hypersensitivity:
Mediators of :
Type I
Types II and III
Type IV

A

Type I = IgE
Types I and II = IgG, IgM
Type IV = Th1

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15
Q
A

Crust
Fissure
Erosions
Maceration
Ulcer
Lichenification
Scale
Atrophy

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16
Q

What provides pressure and vibration sensations respectively ?

A

Pacinian corpuscles, Meissner’s corpuscles

17
Q

Erythropoeitic protoporphyria enzyme

A

Ferrochelatase

18
Q

Lip and tongue swelling 5 minutes after eating a prawn sandwich. What type of hypersensitivity reaction ?
And what is the mediator ?

A

Type I immediate hypersensitivity

Mediated by IgE