Glycopeptides Flashcards
1
Q
Examples of Glycopeptides
A
- Vancomycin
- Telavancin
2
Q
If an infection is systemic, which Glycopeptide would you give and why
A
Parental Vancomycin
(because oral has reduced absorption)
3
Q
Can you use Glycopeptides in Pregnancy
A
No
(unless benefits outweigh risks)
4
Q
What is the dose of Glycopeptides based on
A
Initial: Body Weight
After: Serum Concentration
5
Q
What should the TROUGH concentration be
A
15 to 20mg/L
6
Q
What toxicity do Glycopeptides cause
A
- Nephrotoxicity
- Ototoxicity
7
Q
Side effects of Glycopeptides
A
- red mans syndrome
- steven johnson syndromes
- blood dyscrasia (neutropenia)
- anaphylactoid reaction
8
Q
How to avoid Anaphylactoid reaction
A
rotate site and avoid quick admission
