Glycolysis Steps

Question 1

Step 1

Answer 1

glucose is phosphorylated by hexokinase to glucose-6-P

Question 2

Step 2

Answer 2

Glucose-6-P is isomerized to fructose-6-P by phosphoglucoisomerase.

Question 3

Step 3

Answer 3

Fructose-6-P is phosphorylated to fructose-1,6-BP by phosphofructokinase-1 (PFK-1)

THE RATE LIMITING STEP OF THE ENTIRE PATHWAY

Question 4

Step 4

Answer 4

Fructose-1,6-BP is cleaved to glyceraldehyde-3-P and dihydroxyacetone-P by aldolase

Question 5

Step 5

Answer 5

Dihydroxyactetone-P is isomerized to glyceraldehyde-3-P by triose phosphate isomerase

Question 6

Step 6

Answer 6

G3P is oxidized and phosphorylated to form 1,3-bisphosphoglycerate by glyceraldehyde-3-P dehydrogenase

Question 7

Step 7

Answer 7

1,3-bisphosphoglycerate is converted to 3-phosphoglycerate via substrate level phosphorylation by phosphoglycerate kinase

Question 8

Step 8

Answer 8

phosphoglcyerate mutase causes a phosphoryl shift in 3-phosphoglycerate to form 2-phosphoglycerate

Question 9

Step 9

Answer 9

2-phosphoglycerate is dehydrated by enolase to form phosphoenolpyruvate

Question 10

Step 10

Answer 10

phosphoenolpyruvate is converted to pyruvate by pyruvate kinase