Glycolysis

Question 1

GLUT 1

Answer 1

Found everywhere (ubiquitous)

High Affinity

Erythrocytes, brain, cornea, placenta and cancer cells

Question 2

GLUT 2

Answer 2

Liver and Pancreas

Low Affinity

Question 3

GLUT 3

Answer 3

Neurons

High Affinity

Question 4

GLUT 4

Answer 4

Skeletal muscles, adipose tissue and heart

REGULATED BY INSULIN (Inducible by glucose uptake)

Moderate affinity

Question 5

Tauri Dz biochemical impact

Answer 5

Deficiency in PFK-1

Question 6

95% of glycolysis related anemia is attributed to defects in which enzyme?

Answer 6

Pyruvate Kinase

Question 7

Fanconi Bicket Syndrome is due to mutation in?

Answer 7

GLUT 2 Transport which is a transport for Liver and Pancreas. Can take up glucose, fructose and galactose.

Question 8

Insulin stimulates PFK-1 by mean of ____

Answer 8

Protein phosphatases which dephosphorylates PFK-2

Question 9

Glucagon inactivates PFK-1 by means of ____

Answer 9

Protein Kinase 1 which phosphorylates PFK-2 to inactivate PFK-1

Question 10

Tauri Dz symptoms

Answer 10

Muscle weakness and cramps

Hemolytic anemia

High bilirubin and jaundice

Question 11

Defects related to hemolytic anemia stems from

Answer 11

Ineffective glycolysis

Question 12

Diabetes is impacted by glycolysis due to

Answer 12

mutations in glucokinase

Question 13

GLUT 5

Answer 13

Fructose uptake

Question 14

SGLT1

Answer 14

Glucose/Galactose uptake