Glycolysis Flashcards

1
Q

Glut1 transports glucose where?

A

Brain and Blood

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2
Q

Glut2 transports glucose where?

A

Liver and Pancreas

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3
Q

Glut3 transports glucose where?

A

Neurons

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4
Q

Glut4 transports glucose where?

A

Heart,muscle,fat

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5
Q

Which transporter is regulated by insulin?

A

Glut4

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6
Q

Which transporter has the lowest affinity for glucose?

A

Glut2

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7
Q

Name the 10 steps of glycolysis.

A
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8
Q

Sucrose is a disaccharide of?

A

Glucose and fructose

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9
Q

Lactose is a disaccharide of?

A

glucose and galactose

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10
Q

This enzyme phosphorylates glucose in the first step?

A

Hexokinase

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11
Q

This enzyme functions in the third step of glycolysis?

A

Phosphofructokinase

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12
Q

This enzyme functions in the last step of glycolysis?

A

Pyruvate kinase

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13
Q

Glucokinase functions where?

A

In the liver

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14
Q

what is the most important regulatory step in glycolysis?

A

Phosphofructokinase catalyzed reaction

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15
Q

excessive fructose consumption skips over phosphofructokinase, this leads to what in the liver?

A

excess acetyl CoA converted to fatty acids resulting in fatty liver

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16
Q

Lactose intolerance is caused by a deficiency in which enzyme?

A

lactase

17
Q

Galactosemia is caused by deficiency in what?

A

galactose 1-phosphate uridyl transferase activity.

18
Q

If galactose is not removed from the eye by the transferase then what happens?

A

aldose reductase causes the accumulation of galacitol which leads to cataracts

19
Q

What is the warburg effect?

A

Aerobic glycolysis that some tumors use.

20
Q
A