Glycolysis Flashcards
various biochemical processes responsible for the formation, breakdown and interconversion of carbohydrates in living organisms
Carbohydrate Metabolism
generation of cellular energy
sausage shape
convoluted
Mitochondria
enzyme in mitochondria responsible for production of ATP
ATP Synthase
composition of outermost layer of mitochondria
50% protein
50% lipid
composition of innermost layer of mitochondria
80% protein
20% lipid
beginning of metabolism
digestion
action of salivary amylase
starch & glycogen -> polysaccharides
action of pancreatic amylase
polysaccharides -> disaccharides
action of S.I
disaccharides -> simple sugars
stops enzyme action in stomach
gastric juice
enzymes in S.I
maltase, sucrase, lactase
reaction of digestion of carbohydrates
hydrolysis
has greatest no. of ways to utilize glucose
storage
glucose -> glycogen
releases free glucose from glycogen when blood glucose levels are low
liver
utilizes stored glycogen for synthesis of ATP during exercise
skeletal muscle
reoxidized to continue glycolysis
NADH
Starch + Salivary Amylase +H2O
Maltose + Dextrins
Starch + Pancreatic Amylase + H2O
Maltose + Isomaltose
Maltose + Maltase + H2O
Glucose (2)
Isomaltose + Maltase + H2O
Glucose (2)
Lactose + Lactase + H2O
Glucose + Galactose
Sucrose + Sucrase + H2O
Glucose + Fructose
breakdown of all compounds
catabolism
Common Monosaccharides
glucose
galactose
fructose
Disaccharides
sucrose ( glucose + fructose)
maltose (glucose + glucose)
Lactose (glucose + galactose)
Polysaccharides
Starch Dextrin Cellulose Pectin Glycogen
Absorption of Monosaccharides
Simple Diffusion
Facilitated Transport
Active Transport
Accdg. to concentration gradient
Fructose and pentoses
Simple Diffusion
GLUT5: glucose, galactose and fructose
Facilitated Transport
SGLT (Sodium Glucose Transporter)
glucose and galactose
Active Transport
Pathways for Glucose Utilization
Oxidation
Provides other Compounds
Storage
Excretion in urine
for production of energy
Oxidation
Provides other compounds:
Carbohydrates
Glycerol 3-phosphate
Acetyl CoA
Non essential AA
storage in adipose
triacylglycerol
Major Pathways in oxidation of glucose
Glycolysis
Kreb’s Cycle
Minor Pathways in oxidation of glucose
Hexose monophosphate pathway
Uronic acid pathway
Central roles of glucose
storage
oxidation via glycolysis
oxidation via pentose phosphate pathway
synthesis of structural polymers
storage
glycogen, starch, sucrose
oxidation via glycolysis
pyruvate
oxidation via pentose phosphate pathway
ribose 5-phosphate
synthesis of structural polymers
extracellular matrix
cell wall polysaccharides
- a pathway used by all body cells
- converts glucose to pyruvate
- an example of anaerobic fermentation
- oxygen is not necessary
- mostly endergonic reactions
Glycolysis