Glycolysis Flashcards

1
Q

Glycolysis

A

Breakdown of Glucose; 10 step linear pathway, in cytoplasm; 1 glucose->2 pyruvates +2 atp +2 NADH

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2
Q

Steps 1-5

A

break 1 glucose into 2 glyceraldehyde 3-phosphate fragments - requires 2 atp

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3
Q

Steps 6-10

A

occurs twice for each glucose; produce 2 pyruvate, 4 atp, 2 nadh/h+

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4
Q

Controlled at steps ___, ___, ___

A

1, 3, 10

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5
Q

Step 3 main control

A

atp, citrate negative effectors for phosphofuctokinase, ADP AMP positive effectors, turned off when high in atp and citrate

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6
Q

Step 1

A

Catalyzed by hexokinase, glucose 6-phosphate as negative effector, concentration of glucose 6-phosphate can rise from inhibition of step 3, manufacture of glucose, breakdown of glycogen

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7
Q

Step 10

A

Catalyzed by pyruvate kinase; atp, fructose, 1,6-biphosphate and alanine as negative effectors, 1,6-biphosphate is reactant in step 4

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8
Q

Anaerobic conditions lead to

A

lactate formation

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9
Q

Aerobic conditions lead to

A

Acetyl-CoA formation

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10
Q

Conversion of glucose to lactate under anaerobic conditions is

A

spontaneous; energy released as heat

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