Glycolysis

Question 1

Where does glycolysis occur ?

Answer 1

In the cyptoplasm

Question 2

What are the 4 stages of glycolysis ?

Answer 2

Activation of glucose by phosphorylation

Splitting of the phosphorylated glucose

Oxidation of triose phosphate

Production of ATP

Question 3

What is the ATP yield of glycolysis ?

Answer 3

2 ATP
2 are used in stage 1 to activate glucose
4 produced in stage 4 - substrate level phosphorylation

Question 4

What are the properties of phosphorylated glucose compared to glucose that isn’t phosphorylated

Answer 4

Phosphorylated glucose is more reactive and less activation energy is required for the subsequent reactions

Phosphorylated glucose is polar so less likely to diffuse out of the cellular

Question 5

what happens in glycolysis ?

Answer 5

1: activation of glucose by phosphorylation. The hydrolysis of 2 ATP molecules provides the phosphate. this raises the energy levels of glucose and makes it more reactive

2: the hexose phosphate (phosphorylated glucose) splits into 2 triose phosphates

3: these become oxidised to yield 2 ATP each by substrate level phosphorylation

(dehydrogenation) H atom removed from triose phosphate and added to NAD(coenzyme)

2 pyruvates formed