glycogen storage Flashcards

1
Q

in the liver, glycogenolysis is regulated by

A

hormones, ( by muscle contraction in skeletal muscles)

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2
Q

stimulates glycogenolysis

A

epi

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3
Q

largest amount of glycogen is found

A

in skeletal muscle. ( liver has highest concentration)

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4
Q

highly activated form of glucose which is used for glycogen synthesis

A

UDP glucose

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5
Q

UDP glucose is made from

A

glucose 1p and UTP

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6
Q

makes alpha 1-4 bonds

A

glycogen synthase

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7
Q

glycogen synthase is activated by

A

glucose 6p (inhibits glycogen phosphorylase)

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8
Q

andersons disease

A

defective 4:6 glucosydyltransferase (type IV) liver cirrhosis, death by 5 years.

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9
Q

cori disease

A

defective 4:4 glucosydyltransferase, type III

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10
Q

liver phosphorylase deficiency

A

Her’s disease. type VI, hepatomegaly

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11
Q

muscle phosphorylase deficiency

A

McArdle. type V, exercise induced cramps, rhabdo, brown urine, renal failure.

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