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Step 1: Biochem > Glucose metabolism > Flashcards

Glucose metabolism Flashcards

1
Q

Polyol pathway

A

Glucose –> Sorbitol via Aldose Reductase/NADPH
Sorbitol –> Fructose via Sorbitol dehydrogenase/NAD+

Stuck at sorbitol in retina, renal papilla, and schwann cells

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2
Q

How does alcohol cause hypoglycemia?

A

Increased NADH/NAD+ ratio –> No NAD+ for gluconeogenesis

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Step 1: Biochem (10 decks)

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