Gluconeogenesis Flashcards

1
Q

1st irreversible step

A

Pyruvate –> oxaloacetate

Pyruvate carboxylase
+ B7, ATP, acetyl-CoA in Mitochondria

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2
Q

2nd irreversible step

A

Oxaloacetate –> Phosphoenolpyruvate

PEP carboxykinase
+ GTP

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3
Q

3rd irreversible step

A

F-1,6-bisphosphate –> F-6-phosphate

F-1,6-bisphosphatase
+ citrate
- F-2,6-bisphosphate

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4
Q

4th irreversible step

A

G-6-P –> Glucose

glucose-6-phosphatase

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