Glucose metabolism

Question 1

What chain linkages does glycogen have?

Answer 1

1 to 4

1 to 6

Question 2

Why is the name of the bond between two glucose molecules?

Answer 2

Glyosidic bond

Question 3

Which has more branches

Glycogen or starch?

Answer 3

Glycogen

Question 4

What is Glycogens structure?

How many glucose per chain?
How often does branching ooccur?

Answer 4

3D helical structure

12-14 glucose/chain
Branches occurs every 8-12 glucoses

Question 5

How any glucose molecules make up one glycogen molecule?

Answer 5

120,000

Question 6

What size are glycogens?

Answer 6

around 10-40 nm diameter

Granules= 20-40 molecules

Question 7

Glycogen makes up how much of the liver and muscle mass?

Answer 7

Up to 10% of liver mass

1-2% of muscle

Question 8

Where is glycogen storaged?

Answer 8

Free in the cytoplasm

Question 9

Describe the first 2 steps of glycogenolysis

Answer 9

Glycogen + Pi cofactor-> G1P ( w/ glycogen phosphorylase)

G1P-> G6P ( phosphoglucomutase)

Question 10

What is the general equation for phosphorolysis?

Answer 10

R-O-R’ + HOPO32- -> R-OH + R’-OPO3^2-

Question 11

Why does glycogenolysis use phosphorolysis not glycolysis?

Answer 11

Phosphorolysis does not use ATP.

Question 12

What are the 3 isozymes of phosphorylase?

Answer 12

Muscle mGP
Brain bGP
Liver lGP