Glucocorticosteroids (steroids) Flashcards
Prototype
Hydrocortisone
Ends in
Sone
Primary use
Addisons disease: primary adrenal insufficiency AEB bronzed skin
Long term steroid use: Secondary adrenal insufficiency
Asthma, COPD
UC, Chron’s
Considerations
4-10 days max unless Addison disease, then it’s life (prevents secondary adrenal insufficiency)
Encourage vitamin D
Don’t skip a dose
Take 6-9 am. That’s when cortisol is normally made.
MOA
Stop inflamation
Suppress immune function
Side effects
Too much steroid use: Cushing syndrome:
Acne, GI bleed, ulcers, irritability, increased hunger, increased osteoporosis risk, fat redistribution: buffalo hump, rounded face
Sodium and fluid retention: tachycardia, weight gain
Hyperglycemia
Increased infection risk
Monitor
Weight gain, blood sugar, cushings syndrome, osteoporosis, potassium, GI bleeds, cholesterol levels