Antithyroid Drugs Flashcards
Primary use
Graves disease (Hyperthyroidism): AEB hyperactivity, loosing weight, anxiety, speeds things up, A fib, increased metabolism, tachycardia, increased body temp, bug eyes.
Severe: hashimottos disease
Prototype
Propylthiaurical
MOA
Stops thyroid from making t3 and t4
Side effects
If too much then hypothyroidism symptoms: weight gain, brittle hair, leukopenia, agranulocytosis (rare), slow things down, cold intolerance
Considerations
Administer with foods same time every day
Drink up to 3 L of fluids a day
Avoid iodine containing foods like: shrimp, soy sauce, salt
Signs of efficacy
Sleeping at night
Slight weight gain
Not tachycardic
Montior…
Dizziness, pulse, palpitations, temp changes, tsh, t3, t4
Liver function