Glucocorticoids - specific drugs Flashcards
Short to medium-acting glucocorticoids (4 drugs)
Hydrocortisone
Prednisone
Prednisolone
Methylprednisolone
When is a high-dose therapy of hydrocortisone used?
During surgery in Cushing syndrome
Hydrocortisone - indications
DOC: adrenal insufficiency
CAH
Cushing syndrome-surgery
Ulcerative colitis
When is hydrocortisone adm IV?
Addisonian/adrenal crisis
Hydrocortisone - adverse effects
In addition to effects of glucocorticoids in general, it has salt-retaining activity. This may cause hypertension, loss of potassium and sodium retention.
The synthetic glucocorticoids are used in
Chrousos syndrome (glucocorticoid resistance)
The synthetic glucocorticoids are not used in?
Primary adrenal insufficiency
Glucocorticoids used for systemic treatment (4 drugs)
Prednisolone
Methylprednisolone
Triamcinolone
Bethamethasone
Glucocorticoids with salt-retaining activity (3 drugs)
Hydrocortisone
Prednisone
Prednisolone
Intermediate-acting glucocorticoid (1 drug)
Triamcinolone
Which glucocorticoids can be used for allergic rhinitis?
Triamcinolone Beclomethasone Flunisolide Mometasone furoate Cliclesonide
Long-acting glucocorticoids (3 drugs)
Dexamethasone
Betamethasone
Budesonide
Glucocorticoid with very high anti-inflammatory effect
Dexamethasone
Dexamethasone - indications
Diagnostic: suppression test for Cushing syndrome
Emesis in neoplasms
Long and potent treatment for infl+inf diseases
Glucocorticoid used to mature fetal lungs
Betamethasone
