GLP-1 Agonists Flashcards
What is the MOA of GLP-1 agonists?
Activates GLP-1 receptors
Increases insulin release in response to meals
GLP-1 agonist expected change in A1c
High
GLP-1 agonist dosing frequency
Typically weekly
GLP-1 agonist route of administration
Subcutaneous
GLP-1 agonist ADEs
GI (NVD)
GLP-1 agonist risk of hypoglycemia
Low
GLP-1 agonist impact of weight
Significant weight loss
GLP-1 agonist CV impact
Improves outcomes
GLP-1 agonist renal impact
Improves outcomes
GLP-1 agonist precautions/CIs
Avoid in medullary thyroid cancer
GLP-1 agonist drug interactions
No significant drug interactions
GLP-1 agonist cost
High
GLP-1 agonists affect
Post-prandial blood sugar
GLP-1 agonists clinical pearl
Some agents are branded for weight loss
GLP-1 agonists administration vehicles
Prefilled pens or autoinjectors